ReviewProtoplasma2025
Surviving desiccation: key factors underlying tolerance in prokaryotes and eukaryotes.
Review in Protoplasma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- Plant microbiome engineering: from inoculation to genome editing.Frontiers in microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Water is essential for all forms of life, and its loss triggers a series of protective responses in both prokaryotic and eukaryotic organisms. This review summarizes the fundamental mechanisms that underlie desiccation tolerance, focusing on the phenomenon of anhydrobiosis. Key strategies include osmoprotection, accumulation of compatible solutes such as trehalose and sucrose, protein anti-aggregation, and enhanced antioxidant activity. Osmoadaptation enables cells to regulate osmotic pressure and maintain membrane integrity during water loss. Intrinsically disordered proteins, particularly late embryogenesis abundant (LEA) proteins, contribute to protein stabilization by forming molecular shields under desiccation stress. Furthermore, the upregulation of antioxidant enzymes, such as superoxide dismutase (SOD) and catalase (CAT), mitigates oxidative damage to nucleic acids and proteins. Together, these mechanisms preserve cellular integrity and functionality, facilitating recovery upon rehydration.
Indexed as
Identifiers
41225211What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.