Evidence map›Paper›PMID 41225174›Full record

ArticleSurgical endoscopy2026

Risk factors for bile leakage following laparoscopic cyst excision and hepaticojejunostomy in pediatric choledochal cysts: a retrospective case-control study.

YanBing Huang, YuanBin He, Wen You, XiaoJin Zhuang, DianMing Wu, YiFan Fang, Yu Lin

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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

YanBing Huang *Department of General Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
YuanBin He *Department of General Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Wen YouDepartment of General Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
XiaoJin ZhuangDepartment of Pathology, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
DianMing WuDepartment of General Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
YiFan FangDepartment of General Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China. 494223787@qq.com.
Yu LinDepartment of General Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China. linyu_ping@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLaparoscopic surgery has been accepted as an effective and safe approach for the treatment in pediatric choledochal cysts (CDCs). However, bile leakage remains one of the most severe early postoperative complications. This study aims to identify risk factors for bile leakage following laparoscopic cyst excision and hepaticojejunostomy in pediatric CDCs and optimize perioperative management strategies.

methodsA retrospective study was conducted on children who underwent laparoscopic cyst excision and hepaticojejunostomy at Fujian Children's Hospital between January 2016 and January 2025. Comprehensive clinical data were extracted from institutional electronic medical records. Participants were stratified into bile leakage and non-bile leakage groups. Univariate analysis and multivariate regression models were used to identify risk factors.

resultsA total of 131 patients were included in this study. The median age of included children was 1.8 years (range: 0.1 ~ 14.3), with a male-to-female ratio of 1.0:3.6. There were 14 cases included in the bile leakage groups, with 7 cases (50%) required surgical reintervention. Univariable analysis indicated that bile leakage was associated with preoperative pancreatitis (p = 0.02), cholangitis (p = 0.03), type IV CDCs (p = 0.03), bile duct stones (p = 0.01), and prior biliary surgery (p = 0.02). Multivariable analysis showed that bile duct stones (OR = 4.4, 95% CI 1.0 ~ 18.8) and prior biliary surgery (OR = 5.1, 95% CI 1.1 ~ 23.0) were independent factors that were associated with bile leakage.

conclusionBile duct stones and prior biliary surgery significantly increase the risk of bile leakage in pediatric CDCs following laparoscopic cyst excision and hepaticojejunostomy. Proactive management of biliary inflammation, complete stone clearance, and meticulous surgical techniques are critical for the prevention of complications.

Indexed as

Anastomotic LeakCholedochal CystJejunostomyLaparoscopyPostoperative ComplicationsAdolescentCase-Control StudiesChildChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesRisk FactorsBile leakageCholedochal cystHepaticojejunostomyRisk factors

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.