ArticleEuropean journal of nuclear medicine and molecular imaging2026
Microvascular dysfunction assessed by dynamic spect has a prognostic value in patients with a first acute myocardial infarction in a 3-year follow-up study.
Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the prognostic value of dynamic single-photon emission computed tomography (SPECT) in patients with early acute myocardial infarction (AMI).
methodsSixty-three patients with a first AMI were enrolled. Diagnostic and treatment algorithms were completed in full accordance with standard medical care. Dynamic cadmium-zinc-telluride (CZT) SPECT was performed 7-10 days after AMI. Stress and rest myocardial blood flow (MBF), myocardial flow reserve (MFR), summed stress score (SSS), summed rest score (SRS), and summed difference score (SDS) were evaluated. Based on the occurrence of major adverse cardiac events (MACE) during a three-year follow-up, patients were divided into two groups: (1) MACE- (n = 53) and (2) MACE+ (n = 10).
resultsPatients with MACE were characterized by a higher risk according to the GRACE Scale (p = 0.03) and a more severe condition by the Killip classification (p = 0.001). Dynamic SPECT revealed significantly lower rest MBF in the MACE + group compared to the MACE- group: 0.35 (0.32; 0.45) mL/min/g vs. 0.59 (0.32; 0.81) mL/min/g, respectively (p-value should be added here). Multivariable analysis demonstrated that rest MBF (OR 0.375; 95% CI: 0.15-0.95) and Killip class (OR 7.67; 95% CI: 1.65-35.54) were independent predictors of MACE in patients with a first acute myocardial infarction. A rest MBF value ≤ 0.39 mL/min/g predicted MACE within 3 years with a sensitivity of 70.0% and a specificity of 69.8%.
conclusionDynamic SPECT may have long-term prognostic value for patients with acute myocardial infarction. Rest MBF is a promising additional predictor of MACE when combined with Killip. Further research and multicenter studies are needed to confirm the role of dynamic SPECT. CLINICAL
trial registrationnone.
Indexed as
Identifiers
41225163What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.