ReviewAdvances in experimental medicine and biology2026
Immunomodulation Strategies in Oral Diseases: From Microbiome Manipulation to Pro-resolution Therapies.
Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Host-response and inflammatory processes commonly triggered by dental biofilms play a crucial role in the pathogenesis pathways of prevalent oral diseases, such as periodontitis and implant-related infections, which have been widely explored by scientific evidence. The role of the oral microbiome and the interaction between microorganisms and immune components in the onset and development of such inflammatory conditions has been a primary focus for scientists and clinicians and has opened new possibilities for therapeutic targets to modulate disease progression. Such knowledge and new strategies with the aim of promoting microbial transition to a symbiotic state or modulating immune response have paved the way for innovative approaches to control, treat, and prevent oral diseases. This chapter presents the concepts of immunomodulation related to oral diseases, including the initial changes in resolving the inflammatory response (pro-resolution of inflammation) and how inflammatory processes can be modulated by immune modulatory agents in periodontal and peri-implant diseases.
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