ReviewAdvances in experimental medicine and biology2026
Inflammatory Mediators in Peri-Implantitis: From Pathophysiology to Therapeutic Targets.
Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Association of oxidative stress-related gst gene polymorphisms with periodontitis susceptibility: A systematic review and meta-analysis.Journal of advanced periodontology & implant dentistry · 2026Article
- Early peri-implant crevicular fluid interleukin-1β as a potential predictor of peri-implant diseases: a 12-month prospective study.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peri-implantitis is a complex inflammatory disease affecting dental implants, characterized by microbial involvement, titanium particle release, and host inflammatory reactions. Conventional diagnostic approaches are limited, prompting exploration of biomarkers in saliva and peri-implant crevicular fluid. These include proinflammatory, anti-inflammatory, and bone metabolism-related markers. Advanced perspectives focus on gene polymorphism, proteomics, and single-cell RNA sequencing, which have illuminated detailed cellular interactions and inflammatory pathways unique to peri-implantitis. The future of peri-implantitis management trends toward precision medicine, leveraging genomic data and computational tools for personalized treatment strategies. A comprehensive understanding of peri-implantitis etiology and pathogenesis is crucial for developing effective targeted therapies to benefit patients long-term.
Indexed as
Identifiers
41225110What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.