ArticleNature2026
Estimation and mapping of the missing heritability of human phenotypes.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed.
- Translating functional molecular knowledge into crop-breeding success.Nature reviews. Genetics · 2026Review
- Article
- Genetic architectures of brain-related traits are shaped by strong selective constraints.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Genetic variants in pulmonary hypertension associated with chronic obstructive pulmonary disease.Current opinion in pulmonary medicine · 2026Review
- Beyond years of schooling: Genetic associations across educational milestones in two Norwegian cohorts.PLoS genetics · 2026Article
- Integrating deep learning and pangenomics to recover missing heritability from wild structural variations.BMC genomics · 2026Review
- Structural variants contribute substantially to complex trait heritability.Research square · 2026Article
- Genetic influences on haematopoiesis.Nature reviews. Genetics · 2026Review
- Separating direct, indirect, and parent-of-origin genetic effects in the human population.Cell genomics · 2026Article
- Evolution of quantitative traits with background selection.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
- The Use of Population Isolates to Identify Metabolic Syndrome's Genetic Aetiology.Molecular genetics & genomic medicine · 2026Review
- An empirical Bayes framework for burden and dispersion association tests helps prioritize rare variants associated with Alzheimer's disease.medRxiv : the preprint server for health sciences · 2026Article
- A dish-to-biobank framework links β-cell nutrient-stress programs to genetic and dietary risk for Type 2 Diabetes.bioRxiv : the preprint server for biology · 2026Article
- Hybrid crosses reveal a cell-type-specific landscape of mouse regulatory variation.bioRxiv : the preprint server for biology · 2026Article
- Genetic perspectives on the comorbidity of anxiety and mood disorders with cardiovascular disease.Nature cardiovascular research · 2026Review
- Optimizing phenotype scale improves genetic analyses in large-scale biobanks.bioRxiv : the preprint server for biology · 2026Article
- Genetic factors contributing to atherosclerosis.Current opinion in cardiology · 2026Review
- Combinatorial effects of gene dosage, polygenic background and environment on complex traits.medRxiv : the preprint server for health sciences · 2026Article
- Low genetic risk for coronary artery disease underlies multigenerational longevity and healthy aging.GeroScience · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Pierrick WainschteinIllumina Artificial Intelligence Laboratory, Illumina Inc., San Diego, CA, USA. pwainschtein@illumina.com.ORCID 0000-0002-5203-6481
Yuanxiang ZhangInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-0695-4409
Jeremy SchwartzentruberIllumina Artificial Intelligence Laboratory, Illumina Inc., San Diego, CA, USA.
Irfahan KassamIllumina Artificial Intelligence Laboratory, Illumina Inc., San Diego, CA, USA.ORCID 0000-0002-6150-5614
Julia SidorenkoInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0003-1494-6772
Petko P FizievIllumina Artificial Intelligence Laboratory, Illumina Inc., San Diego, CA, USA.
Huanwei WangInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-6137-3391
Jeremy McRaeIllumina Artificial Intelligence Laboratory, Illumina Inc., San Diego, CA, USA.ORCID 0000-0003-3411-9248
Richard BorderDepartment of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA.ORCID 0000-0002-6293-2968
Noah ZaitlenDepartment of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Sriram SankararamanDepartment of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.ORCID 0000-0003-1586-9641
Michael E GoddardCentre for AgriBioscience, Agriculture Victoria, Bundoora, Victoria, Australia.
Jian ZengInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0001-8801-5220
Peter M VisscherInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-2143-8760
Kyle Kai-How FarhIllumina Artificial Intelligence Laboratory, Illumina Inc., San Diego, CA, USA.ORCID 0000-0001-6947-8537
Loic YengoInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. l.yengo@imb.uq.edu.au.ORCID 0000-0002-4272-9305
Funding
Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7MVANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7MThe Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4MMethods for Genome-wide Association Studies in Admixed PopulationsR01HG006399 · NHGRI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI PRICE, ALKES L · 2011 to 2024
$6.3MModular Automated -80C Sample Storage SystemS10OD025092 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GOLDENRING, JAMES RICHARD · 2019 to 2019
$2.0MAutomated Storage and Retrieval of Biological SystemsS10RR025141 · NCRR · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2008 to 2008
$988kBioVU Plasma Storage EquipmentS10OD017985 · OD · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2014 to 2014
$239kNCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR002243NCRR NIH HHS S10 RR025141NCRR NIH HHS UL1 RR024975NHGRI NIH HHS R01 HG006399NIH HHS S10 OD017985NIH HHS S10 OD025092
Abstract
Rare coding variants shape inter-individual differences in human phenotypes
Indexed as
Genome-Wide Association StudyMultifactorial InheritancePhenotypeQuantitative Trait, HeritableBiological Specimen BanksFemaleGene FrequencyGenome, HumanHumansINDEL MutationMalePedigreePolymorphism, Single NucleotideUnited KingdomWhite PeopleWhole Genome Sequencing
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.