Evidence map›Paper›PMID 41225006›Full record

ArticleNature2026

Potent neutralization of Marburg virus by a vaccine-elicited antibody.

Amin Addetia, Lisa Perruzza, Kaitlin Sprouse, Young-Jun Park, Matthew McCallum, Cameron Stewart, Bianca Partini, Jack T Brown, Alessia Donati, Katja Culap and 10 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Computational design of an ultrapotent deltacoronavirus miniprotein inhibitor.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Amin AddetiaDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Lisa PerruzzaHumabs Biomed, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Kaitlin SprouseDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0003-0007-2226
Young-Jun ParkDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0003-2901-6949
Matthew McCallumDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0001-8398-8330
Cameron StewartDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0002-2786-6256
Bianca PartiniHumabs Biomed, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Jack T BrownDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Alessia DonatiHumabs Biomed, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Katja CulapHumabs Biomed, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.ORCID 0000-0002-0956-0018
Alessio BalmelliHumabs Biomed, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Bhavna ChawlaBIOQUAL, Rockville, MD, USA.
Swagata KarBIOQUAL, Rockville, MD, USA.
Michal GaziTexas BioMedical Research Institute, San Antonio, TX, USA.
Kendra AlfsonTexas BioMedical Research Institute, San Antonio, TX, USA.
Yenny Goez-GaziTexas BioMedical Research Institute, San Antonio, TX, USA.
Ricardo CarrionTexas BioMedical Research Institute, San Antonio, TX, USA.ORCID 0000-0001-7046-7683
Davide CortiHumabs Biomed, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.ORCID 0000-0002-5797-1364
Fabio BenigniHumabs Biomed, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland. fbenigni@vir.bio.
David VeeslerDepartment of Biochemistry, University of Washington, Seattle, WA, USA. dveesler@uw.edu.ORCID 0000-0002-6019-8675

Funding

Centers for Research on Structural Biology of Infectious Diseases: Universal Influenza Vaccine Research75N93022C00036 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI STAKER, BART · 2022 to 2025
$21.7M
Unraveling the bat humoral immune response against zoonotic viruses to guide the design of next-generation therapeuticsDP1AI158186 · NIAID · UNIVERSITY OF WASHINGTON · PI VEESLER, DAVID · 2020 to 2024
$5.4M
NIAID NIH HHS 75N93022C00036NIAID NIH HHS DP1 AI158186
6 · The paper itself

Abstract

Marburg virus (MARV) is a filovirus that causes severe and often lethal haemorrhagic fever

Indexed as

Antibodies, NeutralizingAntibodies, ViralMarburgvirusMarburg Virus DiseaseViral VaccinesAnimalsAntibodies, MonoclonalCryoelectron MicroscopyEpitopesFemaleGlycoproteinsGuinea PigsHumansModels, MolecularMutationPolysaccharidesAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralEpitopesGlycoproteinsGP-protein, Marburg virusPolysaccharidesViral Envelope ProteinsViral Vaccines

Identifiers

PMID41225006
PMCPMC12893919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.