ArticleNature2026
Spatial fibroblast niches define Crohn's fistulae.
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Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
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0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed.
- Building and regenerating intestines by manipulating intestinal stem cells.Nature reviews. Gastroenterology & hepatology · 2026Review
- Epigenetic modulation of stromal cell states underpins pathological tissue niches in Crohn's disease.Nature immunology · 2026Article
- Single-Cell and Spatial Transcriptomics Across Populations With Perianal Fistulizing Crohn's Disease Shows Proinflammatory CD4Cellular and molecular gastroenterology and hepatology · 2026Article
- Tissue-resident colon macrophages shape the microbiome and regulate mucosal healing via ferroportin.Cell reports · 2026Article
- Crohn's Disease: From Immune Dysregulation to Intestinal Damage.Inflammation · 2026Review
- Fibroblasts: a diverse population of cells balancing homeostasis, wound healing, regeneration, inflammation, fibrosis, and cancer across organs.JCI insight · 2026Review
- Local and circulating cytotoxic CD4medRxiv : the preprint server for health sciences · 2026Article
- Impaired keratinization activity in perianal Crohn's fistulas is associated with poor prognosis.Journal of Crohn's & colitis · 2026Article
- Targeting fibroblasts in immune mediated inflammatory diseases: a cellular basis for cure?Rheumatology (Oxford, England) · 2026Review
- Hidden immune memory niches in inflammatory skin diseases.bioRxiv : the preprint server for biology · 2026Article
- Perianal Crohn's Disease in Inflammatory Bowel Disease: Diagnosis, Assessment and Treatment.Life (Basel, Switzerland) · 2026Review
- Spatial multi-omics-guided drug development in inflammatory bowel disease: from mucosal immune niches to precision therapy.Frontiers in immunology · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
38 authors.
Colleen McGregor *Medical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.ORCID 0000-0002-4090-0375
Xiao Qin *Medical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Marta JagielowiczMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Tarun GuptaMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Zinan YinMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Verena LentschMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.ORCID 0000-0001-7440-4604
David Fawkner-CorbettMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.ORCID 0000-0002-5273-3682
Vy Wien LaiMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.ORCID 0009-0007-3625-5995
Paula Gomez CastroMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.ORCID 0009-0002-8620-3695
Esther BridgesMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Chloe Hyun-Jung LeeMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.ORCID 0000-0002-6232-7119
Huei-Wen ChuangMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Lei DengMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Anna AulicinoMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Renuka TeagueOxford Centre for Histopathological Research, Oxford University Hospitals NHS Trust, Oxford, UK.
Sorayya MoradiOxford Centre for Histopathological Research, Oxford University Hospitals NHS Trust, Oxford, UK.ORCID 0009-0005-8098-5210
Jun Sung ParkMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Jeongmin WooMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Kexin XuMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.ORCID 0009-0001-7373-7367
Ruchi TandonDepartment of Cellular Pathology, Oxford University Hospitals NHS Trust, Oxford, UK.
Nicole CianciCenter for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Jan BornscheinMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.ORCID 0000-0001-8673-3122
Ling-Pei HoMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.ORCID 0000-0001-8319-301X
Paulina Siejka-ZielinskaMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.
Zoe ChristoforidouMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK.ORCID 0000-0002-2242-8660
Sarah HillKennedy Institute of Rheumatology, University of Oxford, Oxford, UK.ORCID 0009-0004-2423-591X
Johannes LehmannKennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Rhea KujawaMRC WIMM Advanced Single Cell OMICS Facility, WIMM, Oxford, UK.
Paola Vargas GutierrezMRC WIMM Advanced Single Cell OMICS Facility, WIMM, Oxford, UK.
Carol ChengMRC WIMM Advanced Single Cell OMICS Facility, WIMM, Oxford, UK.
Maria GrecoMRC WIMM Advanced Single Cell OMICS Facility, WIMM, Oxford, UK.
Katherine BakerDepartment of Colorectal Surgery, Oxford University Hospitals NHS Trust, Oxford, UK.
Mark BignellDepartment of Colorectal Surgery, Oxford University Hospitals NHS Trust, Oxford, UK.
Bruce GeorgeDepartment of Colorectal Surgery, Oxford University Hospitals NHS Trust, Oxford, UK.
Eve FryerDepartment of Cellular Pathology, Oxford University Hospitals NHS Trust, Oxford, UK.
Michael ViethInstitute of Pathology, Friedrich-Alexander University Erlangen-Nuremberg, Klinikum Bayreuth, Bayreuth, Germany.
Agne AntanaviciuteMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK. agne.antanaviciute@imm.ox.ac.uk.ORCID 0000-0002-9019-2215
Alison SimmonsMedical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, UK. alison.simmons@imm.ox.ac.uk.ORCID 0000-0003-3454-0710
Funding
Wellcome Trust
Abstract
Crohn's disease often presents with fistulae, abnormal tunnels that connect the intestine to the skin or other organs. Despite their profound effect on morbidity, the molecular basis of fistula formation remains unclear, largely owing to the challenge of capturing intact fistula tracts and their inherent heterogeneity
Indexed as
Crohn DiseaseFibroblastsIntestinal FistulaAnimalsCell MovementCell ProliferationCollagenExtracellular MatrixFemaleFibrosisHumansMacrophagesMaleNeutrophilsStromal CellsCollagen
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.