SynthesisScientific reports2025
A systematic review and meta-analysis of psychological burden in family caregivers of patients with brain tumors.
Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Coping with primary brain tumors together: a scoping review of dyadic psychosocial interventions.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Depression, Anxiety, and Stress After Acquired Brain Injury: The Role of Cognitive Reserve in Patients and Caregivers 'Symptoms.Journal of central nervous system disease · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Family caregivers of brain tumor patients often experience severe psychological problems, with a high prevalence of mental health issues posing a growing challenge in clinical practice. However, the psychological burden borne by these caregivers remains underrecognized. This study aimed to systematically assess the psychological impact on family caregivers of brain tumor patients. Based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA-P) 2020 guidelines, the systematic literature search was conducted across multiple databases (PubMed, PsycINFO, Cochrane Library, MEDLINE, and EMBASE) for studies published up to February 2022. Effect sizes were calculated using random-effects models. The prevalence rates of depression, anxiety, and distress among brain tumor family caregivers were estimated by screening scales and analyzed using meta-analysis. This meta-analysis synthesized data from 15 studies encompassing a total of 974 family caregivers. The pooled prevalence of depression among the caregivers was 37.15% (95% confidence interval (CI) 22.00-52.30%). Additionally, the estimated prevalence of anxiety among the overall sample was 49.47% (95% CI 35.81-63.12%), while 64% (95% CI 54-74%) reported experiencing distress burden. Family caregivers of brain tumor patients exhibit a considerable prevalence of depression, anxiety, and distress. These findings highlight the critical need to assess the psychological burden imposed by brain tumors-particularly malignant cases-on both patients and their caregivers. Such assessment is essential for developing targeted interventions to enhance coping mechanisms and improve mental health support. Future research should further elucidate caregivers' specific psychological challenges to facilitate the implementation of support systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.