ArticleScientific reports2025
Quantitative assessment of benign and malignant bone tumours using synthetic magnetic resonance imaging and diffusion measures.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Diagnostic value of IVIM and DCE-MRI parameters for differentiating benign from malignant bone tumors and their correlations with Ki-67 expression.BMC cancer · 2026Article
- Pediatric acute leukemia mimicking osteomyelitis: clinical and MRI features.Frontiers in oncology · 2026Article
- Exploratory quantitative magnetic resonance imaging characterization of histopathologic subtype heterogeneity in osteosarcoma.Polish journal of radiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Our study aimed to evaluate the feasibility of quantitative magnetic resonance imaging (MRI) for characterising benign and malignant bone tumours. We analysed forty-seven patients with bone tumours who underwent Synthetic MRI with magnetic resonance image complication (MAGIC) and intravoxel incoherent motion (IVIM) sequence imaging performed at 3 T MRI. Based on different pathological results, the patients were divided into benign and malignant bone tumour groups. Two radiologists performed statistical analysis to analyse whether the parameters T1 relaxation time (T1), T2 relaxation time (T2), proton density relaxation time from MAGIC and diffusion-coefficient (D), perfusion-coefficient (D*), perfusion fraction (f) from IVIM to differentiate malignant and benign bone tumours effectively. T1 and D for malignant tumours were significantly lower than benign bone tumours. The combined T1 and D parameters had the best performance for differentiating malignant from benign bone tumours with receiver operating characteristic curves of 0.860. The MAGIC and IVIM techniques can provide quantitative parameters for identifying benign and malignant bone tumours, with the parameters T1 and D demonstrating high diagnostic efficiency. This approach may serve as an effective strategy for improving bone tumour differentiation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.