Evidence map›Paper›PMID 41224803›Full record

ArticleScientific reports2025

Deep learning-based metal artifact reduction in CT for total knee arthroplasty.

Jimin Lee, Hee-Dong Chae, Hyungjoo Cho, Jae Min Kim, Sung Hwan Hong, Ja-Young Choi, Hye Jin Yoo, Sung-Joon Ye

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jimin Lee *Program in Biomedical Radiation Sciences, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea.
Hee-Dong Chae *Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Hyungjoo ChoProgram in Biomedical Radiation Sciences, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea.
Jae Min KimDepartment of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Sung Hwan HongDepartment of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Ja-Young ChoiDepartment of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Hye Jin YooDepartment of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Sung-Joon YeProgram in Biomedical Radiation Sciences, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea. sye@snu.ac.kr.

Funding

Institute of Information & Communications Technology Planning & Evaluation (IITP), South Korea RS-2020-II201336, Artificial Intelligence Graduate School Program(UNIST)National Research Foundation of Korea NRF-2021R1F1A1057818the Ministry of Science and ICT, the Ministry of Trade, Industry and Energy, the Ministry of Health & Welfare, the Ministry of Food and Drug Safety RS-2020-KD000017
6 · The paper itself

Abstract

In this study, we investigated the metal artifact reduction (MAR) performance of a deep learning (DL)-based technique in the evaluation of postoperative CT after total knee arthroplasty (TKA). For the development dataset, we collected CT scans from fifty patients without a metal prosthesis, and for the clinical test dataset, we collected CT scans from 44 patients with a previous history of TKA. We developed a DL-based knee MAR network (KMAR-Net) using 25,000 pairs of simulated images generated from 50 patients using the sinogram handling method. Regarding quantitative analysis, the area, mean attenuation, and standard deviation were calculated for Non-MAR, MAR algorithm for orthopedic implants (O-MAR), and KMAR-Net. For qualitative analysis, overall artifact, bone conspicuity, and soft tissue were compared using visual grading analysis. To additionally validate the feasibility of KMAR-Net under controlled conditions, a phantom study using a CTDI phantom with various metallic inserts and scanning parameters was conducted. KMAR-Net outperformed the projection-completion method regarding the area of dark streak artifacts, mean attenuation, and standard deviation within the artifacts. In the qualitative analysis, KMAR-Net was superior to O-MAR in the overall artifact and soft tissue evaluation, and one of the two readers evaluated it as superior for bone conspicuity (P = 0.080 for reader 1 and P < 0.001 for reader 2). In summary, DL-based KMAR-Net showed superior MAR performance in CT compared to the conventional projection-based method.

Indexed as

Arthroplasty, Replacement, KneeArtifactsDeep LearningMetalsTomography, X-Ray ComputedAgedAlgorithmsFemaleHumansImage Processing, Computer-AssistedKnee ProsthesisMaleMiddle AgedPhantoms, ImagingMetalsArtificial intelligenceCT artifactDeep learningMetal artifact reductionTotal knee arthroplasty

Identifiers

PMID41224803
PMCPMC12612237

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.