Evidence map›Paper›PMID 41224739›Full record

ArticleNature communications2025

A composite motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin.

Devin A Bradburn, Joana C Reis, R Yvette Moreno, Shariq Qayyum, Thibault Viennet, Haribabu Arthanari, Martha S Cyert

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Devin A Bradburn *Department of Biology, Stanford University, Stanford, CA, USA.
Joana C Reis *Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
R Yvette MorenoDepartment of Biology, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-8192-6005
Shariq QayyumDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
Thibault ViennetDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID http://orcid.org/0000-0001-5349-0179
Haribabu ArthanariDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7281-1289
Martha S CyertDepartment of Biology, Stanford University, Stanford, CA, USA. mcyert@stanford.edu.ORCID http://orcid.org/0000-0003-3825-7437

Funding

Supplement to Enhance Wellness and Resiliency in the Graduate EnvironmentT32GM007276 · NIGMS · STANFORD UNIVERSITY · PI MORRISON, ASHBY J. · 1985 to 2023
$32.9M
Systematic elucidation of calcineurin phosphatase signaling in humansR35GM136243 · NIGMS · STANFORD UNIVERSITY · PI Martha S. Cyert · 2020 to 2026
$3.9M
NMR Fingerprinting: Leveraging optimal control pulse design, tailored isotope labeling, and machine learning to study intractable proteinsR01GM136859 · NIGMS · DANA-FARBER CANCER INST · PI ARTHANARI, HARIBABU · 2020 to 2024
$2.4M
NIGMS NIH HHS R01 GM136859NIGMS NIH HHS R35 GM136243NIGMS NIH HHS T32 GM007276
6 · The paper itself

Abstract

Calcineurin, the Ca

Indexed as

CalcineurinIntrinsically Disordered ProteinsAmino Acid MotifsAnimalsCell MembraneHEK293 CellsHumansPhosphorylationProtein BindingSignal TransductionCalcineurinIntrinsically Disordered Proteins

Identifiers

PMID41224739
PMCPMC12612047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.