ArticleInternal medicine (Tokyo, Japan)2026
A Diagnostic Blind Spot in Pseudo-Bartter Syndrome: Aberrant Renin-angiotensin-aldosterone System Activation from Focal Renal Scarring.
Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 40-year-old woman presented with intermittent limb weakness, edema, and persistent hypokalemia. She had a history of recurrent urinary tract infections, but no diuretic or laxative use. Laboratory findings revealed metabolic alkalosis with elevated plasma renin activity and aldosterone levels. The urinary electrolyte response to fluid administration suggested pseudo-Bartter syndrome due to the volume depletion. Abdominal imaging revealed renal scarring, suggesting focal renin release from the ischemic regions. This case highlights the importance of recognizing secondary systemic renin-angiotensin-aldosterone system (RAAS) activation driven by focal renin release in renal scarring. This also illustrates a paradox in which salt and water restriction may worsen RAAS-driven hypokalemia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.