ArticleJournal of affective disorders2026
Unhealthy diet quality as a clinical phenotype in bipolar disorder: A potential treatment target for improved mood and metabolic outcomes.
Article in Journal of affective disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Sodium-glucose cotransporter-2 inhibitors lower risk of kidney replacement therapy and mortality in bipolar disorder with chronic kidney disease.Therapeutic advances in psychopharmacology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
objectivesThis study aimed to investigate unhealthy diet quality in bipolar disorder (BD) and its association with social, metabolic and clinical features in a cohort of well-characterized adult patients with BD.
methodsThis study analyzed a subset of 737 adult participants from the Mayo Clinic Bipolar Disorder Biobank (MCBB) who completed the Rapid Eating Assessment for Participants - Shortened Version (REAP-S) diet quality questionnaire, in which scores <32 indicate an unhealthy diet quality (UDQ). Demographic and clinical variables were compared between individuals with unhealthy and healthy diet quality. Regression models were constructed to explore associations between UDQ and demographic variables, bipolar subtype, chronotype, medical comorbidities, psychotropics and differences in social determinants of health-related stressors.
resultsIndividuals with BD and UDQ (78.8 %) were significantly younger, more likely to be male, and to have a diagnosis of BD-I or schizoaffective bipolar subtype. Additionally, UDQ was significantly associated with evening chronotype, binge eating disorder, comorbid anxiety disorders, obesity, hypertension, and unemployment-related stress. A multivariable logistic regression model identified that a higher education level and older age at BD diagnosis were associated with lower odds of UDQ, while an evening chronotype and comorbid anxiety disorders increased the likelihood of UDQ. LIMITATIONS: The study design limits causality assessment and poses recall bias from self-reported dietary tools.
conclusionsThese findings highlight the importance of investigating diet quality as a potential therapeutic target in the management of BD to improve mood outcomes and mitigate risk of metabolic disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.