Evidence map›Paper›PMID 41223730›Full record

ArticleJournal of preventive medicine and public health = Yebang Uihakhoe chi2025

Associations Between Poor Appetite, Sarcopenia, and Cognitive Function in Community-dwelling Malaysian Older Adults.

Sook Yee Lim, Yoke Mun Chan, Maw Pin Tan, Shahrul Bahyah Kamaruzzaman, Rahimah Ibrahim

Abstract read
In one paragraph

Article in Journal of preventive medicine and public health = Yebang Uihakhoe chi, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sook Yee LimMalaysian Research Institute on Ageing, Universiti Putra Malaysia, Serdang, Malaysia.
Yoke Mun ChanMalaysian Research Institute on Ageing, Universiti Putra Malaysia, Serdang, Malaysia.
Maw Pin TanDepartment of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Shahrul Bahyah KamaruzzamanDepartment of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Rahimah IbrahimMalaysian Research Institute on Ageing, Universiti Putra Malaysia, Serdang, Malaysia.

Funding

Ministry of Higher Education Long Term Research Grant Scheme LRGS/1/2019/UM/01/1/1
6 · The paper itself

Abstract

objectivesThis study aimed to explore the associations between poor appetite, sarcopenia, and cognitive function among Malaysian older adults.

methodsThis nationwide study involved 1086 community-dwelling older adults aged 55 years and above. Poor appetite was defined using a self-reported question, while cognitive function was assessed with the Montreal Cognitive Assessment. Sarcopenia was identified based on handgrip strength, 6-meter gait speed, and muscle mass, in accordance with the Asian Working Group for Sarcopenia 2019 criteria. Associations between poor appetite, sarcopenia, and cognitive function were analyzed using both univariate and multivariate analyses.

resultsMultivariate analysis revealed that handgrip strength (β=0.067, p=0.012) and gait speed (β=1.080, p=0.017) were significantly associated with cognitive function after adjusting for confounders such as age, ethnicity, marital status, education, and alcohol and smoking consumption. However, no significant association was observed between poor appetite and cognitive function, nor was any moderation effect found between poor appetite and sarcopenia-related traits on cognitive function.

conclusionsOur study confirms that low muscle strength and reduced physical performance are significantly associated with an increased risk of cognitive impairment among community-dwelling older adults. These findings underscore the critical importance of muscle strength and physical performance in preserving cognitive function-a decline that is not inevitable with age. Routine screening and early detection of muscle health and cognitive function are essential, and should be followed by intervention strategies targeting muscle health to mitigate cognitive decline in aging populations.

Indexed as

AppetiteCognitionSarcopeniaAgedAged, 80 and overCognitive DysfunctionCross-Sectional StudiesFemaleHand StrengthHumansIndependent LivingMalaysiaMaleMiddle AgedAgedAppetite lossCognitionMuscle strengthSarcopenia

Identifiers

PMID41223730
PMCPMC12690247

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.