Evidence map›Paper›PMID 41223242›Full record

ArticlePloS one2025

Automatic uterus segmentation in transvaginal ultrasound using U-Net and nnU-Net.

Dilara Tank, Bianca G S Schor, Lisa M Trommelen, Judith A F Huirne, Iacer Calixto, Robert A de Leeuw

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Dilara TankDepartment of Obstetrics and Gynecology, Amsterdam University Medical Center, location Vrije Universiteit Amsterdam, Amsterdam, North-Holland, the Netherlands.ORCID https://orcid.org/0009-0006-7252-4753
Bianca G S SchorDepartment of Computer Science, University of Cambridge, Cambridge, United Kingdom.
Lisa M TrommelenDepartment of Obstetrics and Gynecology, Amsterdam University Medical Center, location Vrije Universiteit Amsterdam, Amsterdam, North-Holland, the Netherlands.
Judith A F HuirneDepartment of Obstetrics and Gynecology, Amsterdam University Medical Center, location Vrije Universiteit Amsterdam, Amsterdam, North-Holland, the Netherlands.
Iacer CalixtoDepartment of Medical Informatics, University of Amsterdam, Amsterdam, North-Holland, the Netherlands.
Robert A de LeeuwDepartment of Obstetrics and Gynecology, Amsterdam University Medical Center, location Vrije Universiteit Amsterdam, Amsterdam, North-Holland, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTransvaginal ultrasound (TVUS) is pivotal for diagnosing reproductive pathologies in individuals assigned female at birth, often serving as the primary imaging method for gynecologic evaluation. Despite recent advancements in AI-driven segmentation, its application to gynecological ultrasound still needs further attention. Our study aims to bridge this gap by training and evaluating two state-of-the-art deep learning (DL) segmentation models on TVUS data. MATERIALS AND

methodsAn experienced gynecological expert manually segmented the uterus in our TVUS dataset of 124 patients with adenomyosis, comprising still images (n = 122), video screenshots (n = 472), and 3D volume screenshots (n = 452). Two popular DL segmentation models, U-Net and nnU-Net, were trained on the entire dataset, and each imaging type was trained separately. Optimization for U-Net included varying batch size, image resolution, pre-processing, and augmentation. Model performance was measured using the Dice score (DSC).

resultsU-Net and nnU-Net had good mean segmentation performances on the TVUS uterus segmentation dataset (0.75 to 0.97 DSC). We observed that training on specific imaging types (still images, video screenshots, 3D volume screenshots) tended to yield better segmentation performance than training on the complete dataset for both models. Furthermore, nnU-Net outperformed the U-Net across all imaging types. Lastly, we report the best results using the U-Net model with limited pre-processing and augmentations.

conclusionsTVUS datasets are well-suited for DL-based segmentation. nnU-Net training was faster and yielded higher segmentation performance; thus, it is recommended over manual U-Net tuning. We also recommend creating TVUS datasets that include only one imaging type and are as clutter-free as possible. The nnU-Net strongly benefited from being trained on 3D volume screenshots in our dataset, likely due to their lack of clutter. Further validation is needed to confirm the robustness of these models on TVUS datasets. Our code is available on https://github.com/dilaratank/UtiSeg.

Indexed as

AdenomyosisImage Processing, Computer-AssistedUterusDeep LearningFemaleHumansImaging, Three-DimensionalUltrasonographyVagina

Identifiers

PMID41223242
PMCPMC12611126

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.