ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2026
Body Roundness Index Mediates the Association Between Triglyceride-Glucose Index and Hypertension: A Cross-Sectional Study.
Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- The Triglyceride-Glucose Index and Its Combination with C-Reactive Protein and Anthropometric Indicators as Biomarkers for Hypertension Among Saudi Adults: A Cross-Sectional Survey.Journal of clinical medicine · 2026Article
- Joint associations of anthropometric indices and C-reactive protein-triglyceride-glucose index with incident hypertension: a stratified analysis by blood pressure level from the CHARLS, 2011-2020.Cardiovascular diabetology · 2026Article
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Authors and funding
5 authors.
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Abstract
introductionPrevious studies have shown a correlation between the triglyceride glucose index (TyG) and hypertension, as well as between body roundness index (BRI) and hypertension. However, there is limited research on the bidirectional mediation effects of TyG and BRI on their relationships with hypertension.
aimWe aimed to assess the associations between the TyG with hypertension among participants with different BRI, and examine the potential mediating effect of BRI on the associations between TyG with hypertension.
methodsThis cross-sectional study involved 9,251 middle-aged and elderly individuals from the China Health and Retirement Longitudinal Study. Association between TyG and BRI, and hypertension was examined using multivariable logistic regression, restricted cubic spline analysis, and subgroup analysis. Bidirectional mediation analysis was conducted to determine the direct and indirect effects through BRI and TyG.
resultsAfter adjusting for potential confounders, TyG was associated with a 40% (OR: 1.40; 95% CI: 1.23-1.59) higher risk for hypertension, and BRI was associated with a 33% (OR: 1.33; 95% CI: 1.28-1.38) higher risk for hypertension. A linear association between TyG and hypertension was noted (P
conclusionsBRI appeared to be associated with hypertension risk and played a mediating role in the association between TyG and hypertension. Managing visceral fat and monitoring TyG levels may contribute to alleviating hypertension.
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