Evidence map›Paper›PMID 41222819›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2026

Predictors of 30-day readmission in patients with bloodstream infection: a population-based cohort study.

Kim Oren Gradel, Pavithra Laxsen Anru, Stig Lønberg Nielsen, Sofie Skovmand, Ram Benny Dessau, Jens Kjølseth Møller, Steen Lomborg Andersen, Thøger Gorm Jensen, John Eugenio Coia, Mette Søgaard

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kim Oren GradelCenter for Clinical Epidemiology, and Research Unit of Clinical Epidemiology, Department of Clinical Research, Odense University Hospital, University of Southern Denmark, Odense C, Denmark. kim.gradel@rsyd.dk.ORCID http://orcid.org/0000-0002-5611-2031
Pavithra Laxsen AnruCenter for Clinical Epidemiology, and Research Unit of Clinical Epidemiology, Department of Clinical Research, Odense University Hospital, University of Southern Denmark, Odense C, Denmark.ORCID http://orcid.org/0000-0002-7046-2556
Stig Lønberg NielsenDepartment of Infectious Diseases, and Research Unit of Infectious Diseases, Department of Clinical Research, Odense University Hospital, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0002-7780-7131
Sofie SkovmandDepartment of Clinical Microbiology, Vejle Hospital, University Hospital of Southern Denmark, Vejle, Denmark.ORCID http://orcid.org/0000-0001-9314-1360
Ram Benny DessauDepartment of Clinical Microbiology, Zealand University Hospital, Slagelse, Denmark.ORCID http://orcid.org/0000-0002-1497-6309
Jens Kjølseth MøllerDepartment of Clinical Microbiology, Vejle Hospital, University Hospital of Southern Denmark, Vejle, Denmark.ORCID http://orcid.org/0000-0002-5547-5498
Steen Lomborg AndersenDepartment of Clinical Microbiology, Hospital of Southern Jutland, Sønderborg, Denmark.ORCID http://orcid.org/0009-0009-2157-6555
Thøger Gorm JensenDepartment of Clinical Microbiology, and Research Unit of Clinical Microbiology, Odense University Hospital, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0002-3889-0016
John Eugenio CoiaInstitute of Regional Health Research, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0002-4966-8453
Mette SøgaardDanish Center for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg University Hospital, Aalborg, Denmark.ORCID http://orcid.org/0000-0002-2830-4968

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify predictors of hospital readmissions within 30 days after discharge following a bloodstream infection (BSI).

methodsPopulation-based study of 30,843 patients surviving after their first BSI episode, 2007-2016. Using multivariate competing risk regression analyses, we estimated subhazard ratios (sHRs) and 95% confidence intervals (CIs) for all-cause, infection-related, and unplanned readmissions. Predictors included sex, age, comorbidities, causative microorganisms, length of stay (LOS), and prior hospital admissions.

resultsWithin 30 days of discharge, 9655 patients (31.3%) were readmitted of which 3333 (34.5%) were infection-related and 7725 (80.0%) unplanned. Higher risks of all-cause readmissions were observed for males (sHR [95% CI]: 1.07 [1.03-1.12]), those aged 0-15 years (1.41 [1.26-1.58]), and patients with several comorbidities, especially malignancies and liver diseases (sHR 1.26-2.09). BSIs caused by most microorganisms other than Escherichia coli also predicted an increased readmission risk (sHR 1.11-1.39). LOS in the first, third, and fourth quartiles also predicted a higher readmission risk (sHR 1.26, 1.14, and 1.25, respectively). Patients with prior hospitalization also had a higher readmission risk, within 31-365 (sHR 1.22 [1.16-1.28]) and 1-30 days (1.70 [1.61-1.79]). Results were similar for unplanned readmissions. For infection-related readmissions, only LOS in the first quartile (1-5 days) was associated with a higher readmission risk (1.67 [1.52-1.85]). Over the study period, the median LOS decreased, whereas readmission rates increased.

conclusionNearly one-third of patients discharged alive after a BSI were readmitted within 30 days. Further studies are needed to determine whether some of these readmissions may be avoidable.

Indexed as

BacteremiaPatient ReadmissionSepsisAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCohort StudiesComorbidityFemaleHumansInfantInfant, NewbornLength of StayBloodstream infectionsCohort studyPopulation-based studyReadmissions

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.