Evidence map›Paper›PMID 41222795›Full record

ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2026

Impact of prophylactic drain placement on intra-abdominal infections after gastrectomy: nationwide inpatient database study in Japan.

Keita Kouzu, Shotaro Aso, Yuki Hirano, Hiroki Matsui, Kiyohide Fushimi, Hiroki Kitagawa, Toru Kato, Naoki Yamane, Osahiko Hagiwara, Norikatsu Miyoshi and 7 more

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Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

17 authors.

Keita KouzuDepartment of Surgery, National Defense Medical College, Saitama, Japan.
Shotaro AsoDepartment of Health Services Research, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Yuki HiranoDepartment of Hepatobiliary-Pancreatic and Gastrointestinal Surgery, International University of Health and Welfare School of Medicine, Chiba, Japan.
Hiroki MatsuiDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Kiyohide FushimiDepartment of Health Policy and Informatics, Institute of Science Tokyo Graduate School, Tokyo, Japan.
Hiroki KitagawaDepartment of Infectious Diseases, Hiroshima University Hospital, Hiroshima, Japan.
Toru KatoDepartment of Surgery, Division of Gastroenterological Surgery, Sapporo Medical University, Sapporo, Japan.
Naoki YamaneDepartment of Cardiovascular Surgery, Kawasaki Medical School, Okayama, Japan.
Osahiko HagiwaraDepartment of Surgery, Toho University Ohashi Medical Center, Tokyo, Japan.
Norikatsu MiyoshiDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, Osaka, Japan.
Satoru MatsudaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
Hiroshi MaruyamaDepartment of Surgery, Nippon Medical School Tama Nagayama Hospital, Tokyo, Japan.
Keita MorikaneDivision of Clinical Laboratory and Infection Control, Yamagata University Hospital, Yamagata, Japan.
Junichi SasakiDepartment of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo, Japan.
Hideo YasunagaDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Yuko KitagawaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
Hironori TsujimotoDepartment of Surgery, National Defense Medical College, Saitama, Japan. tsujihi@ndmc.ac.jp.ORCID 0000-0002-2808-4723

Funding

Ministry of Health, Labour and Welfare 23AA2003Ministry of Health, Labour and Welfare 24AA2006
6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the impact of drain placement on the incidence of postoperative complications in patients undergoing gastrectomy.

backgroundThe effectiveness of prophylactic abdominal drain placement in gastrectomy remains unclear. Nevertheless, they are still commonly used following gastrectomy.

methodsWe conducted a retrospective cohort study using a nationwide inpatient database in Japan. Patients who underwent gastrectomy for gastric cancer between January 2014 and March 2022 were included. We applied overlap weighting based on propensity scores to adjust for baseline characteristics. The primary outcome was the incidence of intra-abdominal infections. Secondary outcomes included postoperative percutaneous drainage, in-hospital death, length of hospital stay, and total hospitalization costs.

resultsA total of 217,750 patients met the inclusion criteria, and 196,660 (90.3%) received prophylactic abdominal drains. After overlap weighting, the drain group had a significantly lower incidence of intra-abdominal infections compared to the no-drain group (6.3% vs. 7.6%; 95% confidence interval [CI] - 1.7 to - 1.0). The prophylactic drains were also associated with reduced in-hospital postoperative mortality (0.6% vs. 0.8%; 95% CI - 0.3 to - 0.1). No significant differences were observed between the two groups in postoperative percutaneous drainage or hospital stay duration.

conclusionThis study suggests that prophylactic abdominal drainage was associated with a reduced incidence of intra-abdominal infections after gastrectomy without increasing hospitalization duration or medical costs.

Indexed as

DrainageGastrectomyIntraabdominal InfectionsPostoperative ComplicationsStomach NeoplasmsAgedDatabases, FactualFemaleHospital MortalityHumansIncidenceInpatientsJapanLength of StayMaleMiddle AgedDrain placementGastrectomyGastric cancerIntra-abdominal infectionPostoperative complications

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.