ReviewArchives of microbiology2025
Sand fly gut microbiota in Leishmania transmission: roles, interactions, and paratransgenic prospects.
Review in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leishmaniasis, a vector-borne disease caused by protozoa of the genus Leishmania, is transmitted by the bite of infected female Phlebotomine sand flies. Recent advances highlight the role of Phlebotominae gut microbiota in shaping vector competence and influencing Leishmania development. This review synthesises current knowledge on the diversity and dynamics of sand fly gut microbiota, its modulation by environmental factors and diet, and its interaction with Leishmania parasites. Special focus is placed on the immune and metabolic crosstalk between microbes and both the vector and host, including the role of bacterial components in modulating disease severity. The review also discusses the emerging potential of microbiota-based vector control strategies, particularly paratransgenesis using symbionts such as Wolbachia and Bacillus subtilis and outlines future directions for microbiota-based interventions in sand fly research.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.