Evidence map›Paper›PMID 41222564›Full record

ArticleInorganic chemistry2025

Palladium(II) Complexes with Noncovalent Interactions with DNA: Solution Speciation Controlled by Solvent Identity, pH, and Concentration.

David Fabra, János P Mészáros, Ana I Matesanz, Gabriella Spengler, Francisco Aguilar Rico, Guillermo Moreno-Alcántar, Angela Casini, Éva A Enyedy, Adoración Gómez Quiroga

Abstract read
In one paragraph

Article in Inorganic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David FabraDepartment of Inorganic Chemistry, (IAdChem) Universidad Autónoma de Madrid, Calle Francisco Tomás y Valiente, 7, 28049 Madrid, Spain.ORCID 0000-0001-7382-1668
János P MészárosDepartment of Molecular and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7-8, H-6720 Szeged, Hungary.ORCID 0000-0001-6301-5259
Ana I MatesanzDepartment of Inorganic Chemistry, (IAdChem) Universidad Autónoma de Madrid, Calle Francisco Tomás y Valiente, 7, 28049 Madrid, Spain.ORCID 0000-0002-6113-0656
Gabriella SpenglerDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis u. 6, H-6725 Szeged, Hungary.
Francisco Aguilar RicoDepartment of Inorganic Chemistry, (IAdChem) Universidad Autónoma de Madrid, Calle Francisco Tomás y Valiente, 7, 28049 Madrid, Spain.
Guillermo Moreno-AlcántarChair of Medicinal and Bioinorganic Chemistry, School of Natural Sciences, Department of Chemistry, Technische Universität München, Lichtenbergstrasse 4, 85748 Garching b. München, Germany.ORCID 0000-0001-9836-4694
Angela CasiniChair of Medicinal and Bioinorganic Chemistry, School of Natural Sciences, Department of Chemistry, Technische Universität München, Lichtenbergstrasse 4, 85748 Garching b. München, Germany.ORCID 0000-0003-1599-9542
Éva A EnyedyDepartment of Molecular and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7-8, H-6720 Szeged, Hungary.ORCID 0000-0002-8058-8128
Adoración Gómez QuirogaDepartment of Inorganic Chemistry, (IAdChem) Universidad Autónoma de Madrid, Calle Francisco Tomás y Valiente, 7, 28049 Madrid, Spain.ORCID 0000-0002-9261-9542

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coordination capacity of thiosemicarbazone ligands and their synergism with palladium(II) ions modulate their reactivity, allowing custom design. Using thiosemicarbazones with two potential stable tautomeric forms and imidazole as bioisosteres, we studied how the substitution in the N4 group of the thiosemicarbazone by the

Indexed as

Antineoplastic AgentsCoordination ComplexesDNAPalladiumCell Line, TumorCell ProliferationHumansHydrogen-Ion ConcentrationLigandsMolecular StructureSolventsThiosemicarbazonesAntineoplastic AgentsCoordination ComplexesDNALigandsPalladiumSolventsThiosemicarbazones

Identifiers

PMID41222564
PMCPMC12648656

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.