ArticleJACC. Case reports2026
Right-Sided Endocarditis in Children With Chemotherapy Port Migration: Clinical Challenges and Management Strategies.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
backgroundImplantable chemotherapy ports (ICPs) offer reliable venous access in pediatric oncology but may cause rare, life-threatening complications such as intracardiac dislocation and infective endocarditis (IE). CASE SUMMARY: We report 3 cases of ICP dislocation and IE. Patient 1 was a 4-year-old girl with tricuspid valve destruction who underwent autologous reconstruction using the right atrial appendage. Patient 2 was a 2-year-old girl with a small, nonemboligenic vegetation who was treated with percutaneous port retrieval and antibiotics. Patient 3 was a 22-month-old girl who developed an obstructive pseudonodular mass and experienced sudden cardiac death. DISCUSSION: All patients underwent echocardiography, chest x-ray, and computed tomography imaging. Management included individualized surgical or percutaneous intervention, broad-spectrum antibiotics, and antifungal therapy aligned with febrile neutropenia protocols. This series underscores the need for early detection and tailored treatment after ICP dislocation and IE in children, with autologous valve repair using right atrial appendage offering a growth-compatible option.
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