Trial reportIntegrative cancer therapies
Rhythmic Foot Embrocation According to Wegman/Hauschka for Alleviating Symptoms of Chemotherapy-Induced Peripheral Neuropathy: A Randomized Controlled Trial.
Trial report in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
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Abstract
backgroundChemotherapy-induced peripheral neuropathy (CIPN) in patients treated with platinum-, taxane- or vinca alkaloid-based chemotherapy may cause symptoms such as tingling, numbness, pain, and paresthesia, particularly in patients' hands and feet. This study aimed to evaluate rhythmic embrocation (RE) of the feet according to Wegman/Hauschka in addition to an exercise program (EP) as a complementary treatment for CIPN symptoms.
methodsThis study was a prospective, randomized controlled, 2-center trial. A total of 57 patients with CIPN symptoms were randomly allocated into 2 groups, with 52 patients analyzed: the intervention group (n = 26) and the control group (n = 26). While the intervention group received 3 RE according to Wegman/Hauska and EP within 14 days, the control group performed only EP. CIPN symptoms (
resultsThe mean NRS scores for total CIPN symptoms (tingling, numbness, pain, and cramps) decreased from baseline to 24 hours after the third intervention in both groups. However, the intervention group maintained lower scores 2 weeks later, whereas the scores in the control group returned to baseline levels. A significant time effect was observed for NRS scores with a medium effect size (
conclusionAccording to our study results, RE combined with exercise, particularly after 3 interventions, was more effective in reducing CIPN symptoms in the short-term than was exercise alone; however, symptoms increased again in the absence of interventions (standard care) by the end of the fourth week.
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