Evidence map›Paper›PMID 41222028›Full record

ArticlePediatric pulmonology2025

Adding Early Postnatal Parameters of Ventilation to Prognostic Models for Pulmonary Outcome in Very Preterm Infants.

Birte Staude, Eva-Maria Mair, Maria Zernickel, Antje Westhoff, Rahel Schuler, Frank Oehmke, Harald Ehrhardt

Abstract read
In one paragraph

Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Birte StaudeDivision of Neonatology and Pediatric Intensive Care Medicine, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.ORCID 0000-0003-0772-9219
Eva-Maria MairDivision of Neonatology and Pediatric Intensive Care Medicine, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Maria ZernickelDepartment of Pediatrics and Adolescent Medicine, Centre for Pediatric Clinical Studies, University Medical Center Ulm, Ulm, Germany.
Antje WesthoffDepartment of Pediatrics and Adolescent Medicine, Centre for Pediatric Clinical Studies, University Medical Center Ulm, Ulm, Germany.
Rahel SchulerDepartment of General Pediatrics & Neonatology, Justus Liebig University and Universities of Giessen and Marburg Lung Center, Giessen, Germany.
Frank OehmkeDepartment of Gynecology and Obstetrics, Justus Liebig University of Giessen, Giessen, Germany.
Harald EhrhardtDivision of Neonatology and Pediatric Intensive Care Medicine, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.ORCID 0000-0003-4587-1734

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

aimTo compare discrimination and calibration of prognostic models for pulmonary outcomes in very preterm (VPT) infants born < 32 weeks' gestation when including the mean airway pressure (MAP), the fraction of supplemental oxygen (FiO

methodsIn this retrospective single center study of 168 VPT infants, the mean airway pressure (MAP), the fraction of supplemental oxygen (FiO

resultsThe baseline model demonstrated good calibration (slope 1.02) and discrimination (AUC 0.85) for overall BPD (BPD28), and adding any of the parameters of ventilation resulted only in slight improvement in discrimination (AUC 0.86). For moderate/severe BPD (BPD36), overprediction in the lower extremes and underprediction in the upper extremes became evident for the baseline model. While adding MAP rendered optimal specificity (81%), sensitivity (91%) was highest for FiO

conclusionAdding parameters of ventilation and oxygenation improves baseline models to predict the risk of BPD28 and BPD36 early after birth. Particularly, our data encourage considering MAP as potential predictor in the development of future risk models to improve the prediction accuracy and to solidify early treatment decisions intended to prevent BPD.

Indexed as

Bronchopulmonary DysplasiaInfant, Extremely PrematureRespiration, ArtificialFemaleGestational AgeHumansInfant, NewbornInfant, PrematureMalePrognosisRetrospective StudiesSeverity of Illness Indexbronchopulmonary dysplasiamean airway pressurepretermprognostic modelrespiratory distress syndromerespiratory supportscoresupplemental oxygen

Identifiers

PMID41222028
PMCPMC12606693

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.