Evidence map›Paper›PMID 41221999›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2026

Preterm Birth, Fetal Growth Restriction and Early Postnatal Body Mass Index Normalisation Predict Adult Anthropometry.

Achim Fieß, Alica Hartmann, Eva Mildenberger, Dirk Wackernagel, Julia Winter, Karl J Lackner, Norbert Pfeiffer, Sandra Gißler, Alexander K Schuster

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Article in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Achim FießDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Alica HartmannDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0002-8721-6036
Eva MildenbergerDivision of Neonatology, Department of Pediatrics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Dirk WackernagelDivision of Neonatology, Department of Pediatrics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Julia WinterDivision of Neonatology, Department of Pediatrics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Karl J LacknerInstitute of Clinical Chemistry and Laboratory Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Norbert PfeifferDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Sandra GißlerDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0001-6052-3987
Alexander K SchusterDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

Funding

Else Kröner-Fresenius-StiftungErnst und Berta Grimmke StiftungStufe 1 support of the UM
6 · The paper itself

Abstract

aimThis study assessed the long-term impact of prematurity and fetal growth restriction on adult anthropometric and metabolic outcomes.

methodsIn this retrospective cohort study at the University Medical Center Mainz, Germany, adults aged 18-52 years born between 1969 and 2002 were examined between 2019 and 2021. Participants were classified by gestational age and birth weight percentiles as small (SGA), appropriate (AGA), or large for gestational age (LGA). Adult anthropometric and metabolic parameters were analysed using multivariable regression models in relation to gestational age, fetal growth, and early postnatal BMI normalisation.

resultsAdults born preterm were shorter, lighter and had smaller head circumferences in adulthood than those born at term. Moderately to severely SGA individuals were shorter and lighter and had smaller head circumferences and lower BMI. Participants born LGA were taller and heavier than individuals born AGA. Early postnatal BMI normalisation was associated with improved adult anthropometry in preterm SGA participants only. No significant associations were observed between gestational age or birth weight groups and metabolic outcomes, including metabolic syndrome, hypertension, cholesterol, glucose and triglycerides.

conclusionPrematurity and fetal growth restriction were linked to differences in adult anthropometry, whereas early postnatal BMI normalisation appeared beneficial in preterm SGA individuals.

Indexed as

Body Mass IndexFetal Growth RetardationPremature BirthAdolescentAdultAnthropometryBirth WeightFemaleGestational AgeHumansInfant, NewbornInfant, Small for Gestational AgeMaleMiddle AgedRetrospective StudiesYoung Adultadult anthropometryfetal growth restrictionmetabolic outcomespostnatal body mass indexprematurity

Identifiers

PMID41221999
PMCPMC12890003

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