TMO5 regulates PIN1 polarity convergence and organogenesis downstream of MONOPTEROS in the Arabidopsis shoot.

Abdul Kareem, Carolyn Ohno, Marcus G Heisler

Abstract read

In one paragraph

Article in Development (Cambridge, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Plant Regeneration: Influencing Factors, Regulatory Networks, and Epigenetic Mechanisms.International journal of molecular sciences · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abdul KareemSchool of Life and Environmental Sciences, University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-0976-8652

Carolyn OhnoSchool of Life and Environmental Sciences, University of Sydney, Sydney, NSW 2006, Australia.

Marcus G HeislerSchool of Life and Environmental Sciences, University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0001-5644-8398

Funding

Australian Research Council DP180101149University of Sydney

6 · The paper itself

Abstract

Plants continuously produce lateral organs, such as leaves and flowers, from the shoot apical meristem (SAM). This process is guided by the accumulation of the plant hormone auxin and the polar localization of the efflux protein PIN-FORMED1 (PIN1). The transcription factor MONOPTEROS (MP) plays a crucial role in orienting PIN1 polarity, thereby facilitating auxin-driven organogenesis. In this study, we investigate genes downstream of MP that may regulate PIN1 polarity and organogenesis, discovering that the downstream vascular transcription factor TMO5 can promote PIN1 polarity convergence non-cell-autonomously and that TMO5 and its family members promote organ initiation in the SAM. By examining the role of auxin and cytokinin downstream of these genes, we provide evidence that the TMO5-like genes control PIN1 polarity and drive organogenesis by coordinating multiple hormonal signalling pathways.

Indexed as

ArabidopsisArabidopsis ProteinsDNA-Binding ProteinsMembrane Transport ProteinsOrganogenesis, PlantPlant ShootsTranscription FactorsCell PolarityCytokininsGene Expression Regulation, PlantIndoleacetic AcidsMeristemOrganogenesisSignal TransductionArabidopsis ProteinsCytokininsDNA-Binding ProteinsIndoleacetic AcidsMembrane Transport ProteinsMONOPTEROS protein, ArabidopsisPIN1 protein, ArabidopsisTranscription FactorsAuxinCytokininOrganogenesisPlantTMO5

Identifiers

PMID41221768

DOI10.1242/dev.205255

PMCPMC12752488

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.