Observational studyInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026
Role of vulvovaginal infection in women with short cervix: An observational clinical trial.
Observational study in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveShort cervix (SC) and vulvovaginal infections, such as bacterial vaginosis (BV) and vulvovaginal candidosis (VVC), are known risk factors for preterm birth (PTB). The objective of this study was to investigate whether the combined presence of SC and vulvovaginal infections further elevates the risk of PTB.
methodsWe retrospectively analyzed data from women treated at our institution for SC between June 2021 and March 2024, defined as having a cervical length ≤25 mm prior to 34
resultsAmong 220 eligible women with SC, 157 (71.4%) had no infection, 26 (11.8%) had BV, 33 (15%) had VVC, and four (1.8%) had both BV and VVC. All participants received standard-of-care antibiotic or antifungal treatment. The median gestational age at SC diagnosis was 26
conclusionAdequately treated vulvovaginal infections do not appear to exacerbate the risk of PTB in women with SC, highlighting the importance of routine infection screening and timely treatment to ensure effective mitigation of the potential impact of coexisting infections. Prospective studies are required to confirm our findings and explore the underlying mechanisms.
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