Evidence map›Paper›PMID 41221464›Full record

ReviewMedicine and pharmacy reports2025

Multimodal imaging of cervical lymphadenopathy: diagnostic value and clinical applications.

Dragoș A Țermure, Mîndra E Badea, Delia D Donci, Ovidiu Mureșan, Gabriel E Petre

Abstract readReview
In one paragraph

Review in Medicine and pharmacy reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dragoș A ȚermureDepartment of Maxillofacial Surgery and Radiology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Mîndra E BadeaDepartment of Preventive Dentistry, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Delia D DonciRadiology and Imaging Department, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Ovidiu MureșanDepartment of Maxillofacial Surgery and Radiology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Gabriel E PetreDepartment of Surgery, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cervical lymphadenopathy encompasses a broad spectrum of malignant conditions, including metastatic involvement from head and neck or distant primaries, as well as primary lymphoid malignancies. Accurate imaging assessment is critical for the differential diagnosis, staging, and treatment planning. Advances in imaging now enable detailed evaluation of nodal morphology, vascularity, stiffness, and metabolic activity. Methods: A narrative review was conducted using PubMed, Web of Science, and Google Scholar to identify studies published between January 2015 and June 2025 on imaging evaluation of cervical lymphadenopathy. The diagnostic performance, strengths, and limitations of various imaging techniques were summarized, with emphasis on recent advances and multimodal strategies. Results: Conventional ultrasonography remains the first-line modality for superficial nodes, with Doppler and elastography improving characterization. Shear wave elastography offers quantitative stiffness assessment, enhancing specificity when combined with grayscale ultrasonography. Computed tomography and magnetic resonance imaging provide cross-sectional evaluation of deep or inaccessible nodal levels, with the latter offering superior soft-tissue contrast and functional techniques such as diffusion-weighted imaging. Fluorodeoxyglucose positron emission tomography contributes with metabolic information, improving detection of occult metastases and aiding systemic staging. No single modality is definitive; combined approaches yield higher accuracy and better surgical planning. Emerging technologies, including image fusion, and radiomics, show promise for refining diagnosis. Conclusion: An integrated, multimodal imaging approach optimizes the evaluation of cervical lymph node metastases. Future developments in functional imaging, quantitative analysis, and artificial intelligence may further enhance diagnostic precision and enable personalized management strategies.

Indexed as

cervical lymphadenopathyhead and necklymph node metastasismultimodality imaging

Identifiers

PMID41221464
PMCPMC12600073

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.