ArticleCureus2025
Cystoid Macular Edema Secondary to Acute Retinal Necrosis: The Role of Fundus Fluorescein Angiography in Guiding Treatment.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cystoid macular edema (CME) is an uncommon but vision-threatening sequelae of acute retinal necrosis (ARN). We report a patient who developed CME following vitreoretinal surgery for ARN-associated retinal detachment. Multimodal imaging, particularly fundus fluorescein angiography (FFA), revealed diffuse capillary leakage suggestive of persistent retinal vascular inflammation. Initial therapy with topical interferon alpha-2b yielded no anatomical or visual benefit. In contrast, intravitreal sustained-release dexamethasone resulted in rapid resolution of CME and significant visual improvement without reactivation of viral retinitis. This case highlights the potential role of FFA in identifying retinal vascular leakage predictive of treatment response, thereby guiding the treatment. Careful monitoring remains essential given the risk of viral reactivation with intravitreal corticosteroids.
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Registered trials
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