ArticleTherapeutic advances in gastrointestinal endoscopy
Evaluating the diagnostic value of double-balloon enteroscopy combined with endoscopic ultrasonography for primary small intestinal lymphoma.
Article in Therapeutic advances in gastrointestinal endoscopy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Primary small intestinal lymphoma (PSIL) is a rare malignancy with heterogeneous clinical and pathological features, making accurate diagnosis challenging. Objectives: To investigate the clinical value of double-balloon enteroscopy (DBE) combined with endoscopic ultrasonography (EUS) in the diagnosis of small intestinal lymphoma. Design: Retrospective cohort study. Methods: We retrospectively reviewed 21 patients with pathologically confirmed PSIL who underwent both DBE and EUS at the Department of Small Intestinal Endoscopy, The Sixth Affiliated Hospital of Sun Yat-sen University, between September 2022 and May 2025. Clinical data were collected and analyzed in combination with pathological findings. Results: A total of 21 patients were included (12 males, 9 females; median age of 52 years, range 31-87 years. Subtypes of B-cell lymphomas included diffuse large B-cell lymphoma ( Conclusion: DBE combined with EUS provides complementary morphological and structural information for the diagnosis of PSIL, improving clinical recognition and subtype characterization. Future multicenter studies with larger cohorts are warranted to validate these findings and establish standardized diagnostic protocols.
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