Evidence map›Paper›PMID 41221375›Full record

ArticleCase reports in critical care2025

Endoscopic Variceal Therapy With Multisystemic Glue Embolism: A Case Report and Narrative Review of a Rare but Severe Complication.

Monica Penati, Silvia Lazzaroni, Marine Neury, Karim Bendjelid

Abstract read
In one paragraph

Article in Case reports in critical care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Monica PenatiIntensive Care Service, Department of Acute Medicine, Geneva University Hospitals, Geneva, Switzerland, hug-ge.ch.ORCID https://orcid.org/0009-0003-8541-1043
Silvia LazzaroniIntensive Care Service, Department of Acute Medicine, Geneva University Hospitals, Geneva, Switzerland, hug-ge.ch.
Marine NeuryDepartment of Clinical Pathology, Geneva University Hospitals, Geneva, Switzerland, hug-ge.ch.
Karim BendjelidIntensive Care Service, Department of Acute Medicine, Geneva University Hospitals, Geneva, Switzerland, hug-ge.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastroesophageal variceal bleeding is a life-threatening complication of portal hypertension in patients with cirrhosis. Endoscopic cyanoacrylate injection is an established therapy for variceal hemorrhage, but it may lead to rare systemic complications, including glue embolization. The authors report the case of a patient with decompensated cirrhosis who developed acute gastroesophageal variceal bleeding, managed with endoscopic variceal ligation and cyanoacrylate injection. Postprocedural investigations revealed multiple emboli involving the cerebral, pulmonary, coronary, and renal vascular territories. The present case report and review of the literature highlight the need for increased awareness of glue embolization as a potential adverse effect of cyanoacrylate therapy. Careful patient selection, refined endoscopic technique, and close postprocedure monitoring are essential to minimizing the risks of embolization, reducing complications and optimizing outcomes.

Indexed as

cyanoacrylate glue embolizationdecompensated cirrhosisgastroesophageal variceal bleeding

Identifiers

PMID41221375
PMCPMC12598399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.