Evidence map›Paper›PMID 41221337›Full record

ReviewAnnals of joint2025

Current evidence on medial unicompartmental knee arthroplasty in patients 60 and younger: a narrative review.

Mina Entessari, Ameen Barghi, Azra Dees, Robert Stratta, Chukwuweike Gwam, Morgan Noel, Molly Hartzler, John Hubbard

Abstract readReview
In one paragraph

Review in Annals of joint, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mina EntessariDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Health, Winston-Salem, NC, USA.
Ameen BarghiDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Health, Winston-Salem, NC, USA.
Azra DeesDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Health, Winston-Salem, NC, USA.
Robert StrattaDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Health, Winston-Salem, NC, USA.
Chukwuweike GwamDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Health, Winston-Salem, NC, USA.
Morgan NoelDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Health, Winston-Salem, NC, USA.
Molly HartzlerDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Health, Winston-Salem, NC, USA.
John HubbardDepartment of Orthopaedic Surgery and Rehabilitation, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Health, Winston-Salem, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Knee osteoarthritis (OA) is a debilitating condition that significantly impacts mobility and quality of life, particularly in younger, active patients. Medial unicompartmental knee arthroplasty (UKA) is becoming increasingly utilized as a joint-preserving alternative to total knee arthroplasty (TKA) for treating isolated medial compartment OA. This review evaluates current evidence on medial UKA in patients age 60 years or younger, assessing survivability, functional outcomes, and return to activity rates to provide insight into its viability for this patient population. Methods: A literature search was conducted using PubMed, MEDLINE, SPORTDiscus identifying studies published from 2015 to 2025 evaluating outcomes of medial UKA. Inclusion criteria encompassed original studies in English that focused on medial UKA for knee OA in patients aged ≤60 years and studies that provided separate age-stratified data for this subgroup. Exclusion criteria included review articles, case reports, studies including concomitant procedures, and those analyzing lateral UKA, patellofemoral joint arthroplasty or patients >60 years of age. A total of 19 studies were selected, and the outcome variables of interest included implant survivability, patient-reported outcomes, range of motion (ROM), and return to activity. Key Content and Findings: Medial UKA offers advantages over TKA, such as bone preservation, rapid recovery, and improved knee kinematics. Studies reported survivorship rates exceeding 90% at 10 and 15 years, with improved patient-reported outcomes and ROM. Short-term return-to-activity rates were high, with over 90% of patients resuming physical activity postoperatively. However, concerns regarding longer-term implant durability and performance under high functional demands are still present, particularly in young, athletic individuals engaging in high-impact sports. Conclusions: Overall, medial UKA is a promising option for patients age 60 years and younger with isolated medial compartment OA, offering good long-term implant survivability and functional outcomes, relatively low complication rates and high rates of short-term return to activity. Future studies should review longer-term outcomes of medial UKA in patients age 60 years and younger.

Indexed as

activityknee osteoarthritis (knee OA)Medial unicompartmental knee arthroplasty (medial UKA)sports

Identifiers

PMID41221337
PMCPMC12598422

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.