Evidence map›Paper›PMID 41221322›Full record

ArticleBMJ public health2024

Integrating SARS-CoV-2 rapid antigen testing in maternal, neonatal and child health, HIV, and TB clinics in Kenya and Cameroon: outcomes from the Catalysing COVID-19 Action Project.

Boris K Tchounga, Nelia Hoffman, Rose Masaba, Tatiana Djikeussi, James Ndimbii, Elvis Moma, Sharee Pearson, Evallyne Sikuku, Virginia Gitau, Shabir Argaw and 10 more

Registry-linked trialAbstract read
In one paragraph

Article in BMJ public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05498727 (Assessing the Effectiveness of Integration of Rapid Antigen Testing for SARS-CoV-2 in MNCH, HIV and TB Services in Cameroon and Kenya), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05498727 completednot on this map

Assessing the Effectiveness of Integration of Rapid Antigen Testing for SARS-CoV-2 in MNCH, HIV and TB Services in Cameroon and Kenya: A Pre- and Post- Implementation Evaluation (Effectiveness Study)

Typeobservational_patient_registrySponsorElizabeth Glaser Pediatric AIDS FoundationRan2022 to 2023Enrolled527,184ConditionsCOVID-19ArmsIntegration of SARS-CoV 2 Testing in HIV, MNCH and TB Clinics
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Boris K TchoungaElizabeth Glaser Pediatric AIDS Foundation, Yaoundé, Cameroon.ORCID 0000-0002-8747-9610
Nelia HoffmanElizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia, USA.
Rose MasabaResearch, Elizabeth Glaser Pediatric AIDS Foundation, Nairobi, Kenya.ORCID 0000-0003-1801-7938
Tatiana DjikeussiElizabeth Glaser Pediatric AIDS Foundation, Yaoundé, Cameroon.ORCID 0009-0001-9634-8532
James NdimbiiResearch, Elizabeth Glaser Pediatric AIDS Foundation, Nairobi, Kenya.
Elvis MomaElizabeth Glaser Pediatric AIDS Foundation, Yaoundé, Cameroon.
Sharee PearsonElizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia, USA.
Evallyne SikukuResearch, Elizabeth Glaser Pediatric AIDS Foundation, Nairobi, Kenya.
Virginia GitauResearch, Elizabeth Glaser Pediatric AIDS Foundation, Nairobi, Kenya.
Shabir ArgawElizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia, USA.
Patrice TchendjouElizabeth Glaser Pediatric AIDS Foundation, Yaoundé, Cameroon.
Stephen SiambaResearch, Elizabeth Glaser Pediatric AIDS Foundation, Nairobi, Kenya.
Njoki KimaniDepartment of Health, Kiambu County Government, Kiambu, UK.
Anne-Cecile Zoung-Kanyi BissekDivision of Operation Research in Health, Ministry of Public Health, Yaounde, Cameroon.
Joseph FokamPublic Health Emergencies Operations Coordination Centre, Ministry of Public Health, Yaounde, Cameroon.
Appolinaire TiamElizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia, USA.
Aida YemaneberhanElizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia, USA.
Laura GuayElizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia, USA.
Nilesh Balbhadra BhattElizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia, USA.ORCID 0000-0002-8389-7786
Rhoderick MachekanoElizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Early diagnosis of SARS-CoV-2 infection is key to preventing severe disease and poor outcomes in vulnerable populations, such as pregnant women and people living with HIV or diagnosed with tuberculosis (TB). We assessed outcomes achieved with the integration of SARS-CoV-2 antigen-detecting rapid diagnostic testing (Ag-RDT) into maternal, neonatal and child health (MNCH); HIV and TB clinics in the Catalysing COVID-19 Action project. Methods: Screening and testing for SARS-CoV-2 per national guidelines were integrated into MNCH, HIV and TB clinics in 50 health facilities in Cameroon and Kenya. In Cameroon, screening and testing were done by existing facility staff, while in Kenya, additional community workers and laboratory staff were involved. Clients aged >2 years attending MNCH, HIV and TB clinics between May and October 2022 were included in the study. We estimated the proportion of participants screened, tested and tested positive; calculated the SARS-CoV-2 case detection rate per 1000 attendees and determined factors associated with screening, testing and positivity. Results: Overall, 528 567 attendee visits were reported in Cameroon (282 404) and Kenya (246 163), with screening for SARS-CoV-2 performed in 256 049 (48.4%), showing substantive variations between countries (62.6% in Cameroon and 32.2% in Kenya). Among the 256 049 screened, 19 013 (7.4%) were eligible for testing (9.0% in Cameroon and 3.9% in Kenya), of whom 12 934 (68.0%) were tested for SARS-CoV-2 including 9866/15 934 (61.9%) in Cameroon and 3068/3079 (96.6%) in Kenya. A total of 390 (3.0%) positive tests were identified (329/9866, 3.3%, in Cameroon and 61/3068, 2.0%, in Kenya). Country integration strategy, facility level, setting and clinic were independently associated with screening and testing. Conclusions: Integration of SARS-CoV-2 Ag-RDT in MNCH, HIV and TB clinics in both countries allowed detection of SARS-CoV-2 cases among vulnerable populations. Integration strategies should consider facility settings and additional human resources in high-volume facilities to improve screening and testing proportions. Trial registration number: NCT05498727.

Indexed as

COVID-19HIVPublic Health PracticeSARS-CoV-2

Identifiers

PMID41221322
PMCPMC12599119

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.