Evidence map›Paper›PMID 41221265›Full record

ArticleFrontiers in aging neuroscience2025

Multimodal radiomics of cerebellar subregions for machine learning-driven Alzheimer's disease diagnosis.

Xinqing Hao, Ying Li, Xiulin Wang, Changjun Ma, Ruichen Liu, Yang Jiao, Chunbo Dong, Jing Liu

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinqing Hao *Stem Cell Clinical Research Center, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Ying Li *Stem Cell Clinical Research Center, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Xiulin WangStem Cell Clinical Research Center, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Changjun MaStem Cell Clinical Research Center, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Ruichen LiuStem Cell Clinical Research Center, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yang JiaoDepartment of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Chunbo DongDepartment of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jing LiuStem Cell Clinical Research Center, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to develop a machine learning model based on multimodal radiomics features from cerebellar subregions, utilizing the complementarity of cerebellar structural and metabolic imaging data for accurate diagnosis of Alzheimer's disease (AD). Methods: A total of 164 cognitively normal (CN) subjects and 146 AD patients from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database were included. All participants had 3DT1-weighted magnetic resonance imaging (3DT1W MRI) and [ Results: All three models could effectively diagnose AD, with the multimodal model showing the best performance. In the independent test set, the multimodal model achieved an AUC of 0.903, which was higher than the single-modality models based on [ Conclusion: The multimodal radiomics model based on cerebellar subregions, which integrates [

Indexed as

[18F]FDG PET3DT1W MRIAlzheimer’s diseasecerebellummachine learningradiomics

Identifiers

PMID41221265
PMCPMC12598022

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.