Evidence map›Paper›PMID 41221206›Full record

ArticleDEN open2026

Scheduled Inside Plastic Stent Exchange Prevents Cholangitis and Reduces Unplanned Hospitalization in Patients With Unresectable Malignant Hilar Biliary Obstruction.

Joji Muramatsu, Kazuma Ishikawa, Norito Suzuki, Tomohiro Kubo, Makoto Yoshida, Ginji Omori, Ryo Ito, Shogo Miura, Kohichi Takada

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joji MuramatsuDivision of Medical Oncology, Department of Internal Medicine Sapporo Medical University School of Medicine Hokkaido Japan.ORCID https://orcid.org/0000-0002-7711-5450
Kazuma IshikawaDivision of Medical Oncology, Department of Internal Medicine Sapporo Medical University School of Medicine Hokkaido Japan.ORCID https://orcid.org/0000-0002-4582-042X
Norito SuzukiDivision of Medical Oncology, Department of Internal Medicine Sapporo Medical University School of Medicine Hokkaido Japan.
Tomohiro KuboDivision of Medical Oncology, Department of Internal Medicine Sapporo Medical University School of Medicine Hokkaido Japan.ORCID https://orcid.org/0000-0002-5585-0972
Makoto YoshidaDivision of Medical Oncology, Department of Internal Medicine Sapporo Medical University School of Medicine Hokkaido Japan.ORCID https://orcid.org/0000-0001-8013-9712
Ginji OmoriDepartment of Gastroenterology Oji General Hospital Hokkaido Japan.
Ryo ItoDepartment of Gastroenterology Otaru Ekisaikai Hospital Hokkaido Japan.
Shogo MiuraDepartment of Gastroenterology Rumoi City Hospital Hokkaido Japan.
Kohichi TakadaDivision of Medical Oncology, Department of Internal Medicine Sapporo Medical University School of Medicine Hokkaido Japan.ORCID https://orcid.org/0000-0002-1393-9442

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To prevent cholangitis in patients with unresectable malignant hilar biliary obstruction (MHBO), we recently implemented scheduled inside plastic stent (IS) exchange every 2-4 months. This study aimed to evaluate whether this strategy prevents cholangitis onset and reduces unplanned hospitalizations without increasing adverse events. Methods: This retrospective single-center study included patients with unresectable MHBO who underwent IS placement between 2011 and 2023. Patients were divided into two groups: those who underwent scheduled IS exchange (scheduled group, Results: Median duration of unplanned hospitalizations was significantly shorter in the scheduled group compared to the on-demand group (0 days [range: 0-83] vs. 38.5 days [0-140], Conclusions: Scheduled IS exchange delays the onset of cholangitis and reduces the duration of unplanned hospitalizations without increasing adverse events.

Indexed as

biliary stentbiliary tract cancercholangitisERCPscheduled stent exchange

Identifiers

PMID41221206
PMCPMC12599539

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.