ReviewClinical and experimental vaccine research2025
An updated review of Zika virus vaccine development.
Review in Clinical and experimental vaccine research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zika virus (ZIKV) infection as a cause of microcephaly and Guillain-Barré syndrome gained international attention during the 2015-2016 ZIKV epidemic in the Americas. However, over ten years later, there are still no approved ZIKV vaccines, leaving people worldwide defenseless against continued disease spread and potential outbreaks. Prospects for the assessment, licensing, and commercial viability of ZIKV vaccines are complicated by the low incidence of the virus infection at the moment and the uncertainty of future outbreaks. Here, we highlight recent advances in various vaccine platforms that have been developed against ZIKV, including inactivated vaccines, live-attenuated vaccines, DNA vaccines, mRNA vaccines, viral vector vaccines, and recombinant subunit vaccines, with several candidates progressing into clinical trials. This review provides an overview of the current status of ZIKV vaccine development and emphasize how these multiple vaccine platforms can be a powerful tool to react quickly to future pandemics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.