Evidence map›Paper›PMID 41221132›Full record

ReviewBiomedical reports2026

Comprehensive overview of alternative medicine in the treatment of ankylosing spondylitis: Symptoms, pathogenesis, diagnosis and treatments (Review).

So Yeon Park, Min Seok Kwon, Sunju So, La Yoon Choi, Dae Yong Kim, Mi Hye Kim

Abstract readReview
In one paragraph

Review in Biomedical reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

So Yeon ParkDepartment of Korean Medicine, College of Korean Medicine, Woosuk University, Jeonju, Jeollabuk-do 54986, Republic of Korea.
Min Seok KwonDepartment of Korean Medicine, College of Korean Medicine, Woosuk University, Jeonju, Jeollabuk-do 54986, Republic of Korea.
Sunju SoDepartment of Korean Medicine, College of Korean Medicine, Woosuk University, Jeonju, Jeollabuk-do 54986, Republic of Korea.
La Yoon ChoiDepartment of Korean Medicine, College of Korean Medicine, Woosuk University, Jeonju, Jeollabuk-do 54986, Republic of Korea.
Dae Yong KimDepartment of Korean Medicine, College of Korean Medicine, Woosuk University, Jeonju, Jeollabuk-do 54986, Republic of Korea.
Mi Hye KimDepartment of Korean Medicine, College of Korean Medicine, Woosuk University, Jeonju, Jeollabuk-do 54986, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ankylosing spondylitis (AS) is an autoimmune disease characterized by chronic inflammation in the sacroiliac joints and cartilage, resulting in symptoms such as back pain, morning stiffness, sacroiliitis, and extra-articular manifestations. Several drugs reduce the inflammatory response, such as nonsteroidal anti-inflammatory drugs, and disease-modifying antirheumatic drugs. However, the adverse effects and high costs associated with drug therapy highlight the need for complementary treatments. In the present review, significant alternative and complementary remedies for the treatment of AS are examined to provide broader insight. PubMed and Google Scholar were searched for alternative and complementary treatments for AS, using the keywords 'ankylosing spondylitis', 'spondyloarthropathy', 'oriental medicine', 'herbs', and 'therapy'. The symptoms and underlying pathogenesis were described based on diagnostic methods, including principal criteria and radiographic findings. In addition, current remedies for AS, including exercise and pharmacological treatments, were reviewed alongside evidence indicating that alternative therapies, such as moxibustion, decoctions, herbal medicines, and plant-derived compounds, may regulate inflammation, oxidative stress, and abnormal osteogenesis in AS. Given the risks associated with drug use, herbal remedies, including decoctions, formulations, individual herbal extracts, and compounds isolated from herbs, may represent promising therapeutic options for managing the progression of AS. Further large-scale studies, building on cell- and animal-level research, are required to validate the efficacy of herbal medicines.

Indexed as

alternative and complementary medicineankylosing spondylitisherbal medicineHLA-B27IL-23/IL-17 axis

Identifiers

PMID41221132
PMCPMC12598527

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.