Evidence map›Paper›PMID 41221131›Full record

ArticleBiomedical reports2026

Unveiling the gut connection: Exploring the link between microbiota and type 1 diabetes onset in pediatric patients.

Amalia Ioana Arhire, Teodora Papuc, Sorin Ioacără, Gratiela Gradisteanu Pircalabioru, Carmen Gabriela Barbu

Abstract read
In one paragraph

Article in Biomedical reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amalia Ioana ArhireDepartment of General Medicine, The University of Medicine and Pharmacy 'Carol Davila', 020021 Bucharest, Romania.
Teodora PapucDepartment of General Medicine, The University of Medicine and Pharmacy 'Carol Davila', 020021 Bucharest, Romania.
Sorin IoacărăDepartment of General Medicine, The University of Medicine and Pharmacy 'Carol Davila', 020021 Bucharest, Romania.
Gratiela Gradisteanu PircalabioruDepartment of Botany and Microbiology, Faculty of Biology, University of Bucharest, 050095 Bucharest, Romania.
Carmen Gabriela BarbuDepartment of General Medicine, The University of Medicine and Pharmacy 'Carol Davila', 020021 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increasing occurrence of type 1 diabetes mellitus (T1DM) in younger individuals, it is important to identifying contributing factors. A retrospective case control pilot study involving 31 children within the first 6 months after diagnosis, was conducted in the Elias Hospital in Bucharest, Romania) between January 2019- December 2021. Spearman correlation analysis was performed, evaluating the association between microbiota and early onset T1DM, high-level onset glycaemia, ketoacidosis, thyroid autoimmunity and clinical parameters involving growth. Gut dysbiosis with an overabundance of bacteria and fungi was observed compared with the healthy control group.

Indexed as

dysbiosismicrobiotapediatric patienttype 1 diabetes

Identifiers

PMID41221131
PMCPMC12598922

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.