Evidence map›Paper›PMID 41221103›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2025

An Investigation on Cross-Tracer Generalizability of Deep Learning-based PET Attenuation Correction.

Jun Hou, Tianqi Chen, Yinchi Zhou, Xiongchao Chen, Huidong Xie, Qiong Liu, Menghua Xia, Vladimir Y Panin, Takuya Toyonaga, Chi Liu and 1 more

Abstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Beyond CT: Attenuation correction for stand-alone brain PET.Zeitschrift fur medizinische Physik · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jun HouJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.
Tianqi ChenJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.
Yinchi ZhouJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.
Xiongchao ChenJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.
Huidong XieJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.
Qiong LiuJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.
Menghua XiaJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.
Vladimir Y PaninJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.
Takuya ToyonagaJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.
Chi LiuJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.
Bo ZhouJ. Hou and T. Chen are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Y. Zhou, X. Chen, H. Xie, Q. Liu, and M. Xia are with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. V. Y. Panin is with Siemens Medical Solutions USA Inc, Knoxville, TN, USA. T. Toyonaga is with the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. C. Liu is with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA. B. Zhou is with the Department of Radiology, Northwestern University, Chicago, IL, 60611, USA, and the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA.

Funding

Quantitative Low-Dose PET ImagingR01EB025468 · NIBIB · YALE UNIVERSITY · PI CARSON, RICHARD E., LIU, CHI · 2018 to 2022
$3.2M
Multi-Center Academic-Industrial Partnership for Personalized Al-Enabled High Count PETR01CA275188 · NCI · YALE UNIVERSITY · PI RAMSEY D. BADAWI, Georges El Fakhri · 2023 to 2026
$2.5M
NCI NIH HHS R01 CA275188NIBIB NIH HHS R01 EB025468
6 · The paper itself

Abstract

Attenuation correction (AC) is a critical step to ensure accurate quantitative PET imaging. To eliminate the radiation dose from CT, deep learning (DL)-based methods have been extensively investigated to generate the CT-equivalent attenuation map (

Identifiers

PMID41221103
PMCPMC12599847

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.