Evidence map›Paper›PMID 41220901›Full record

ArticleJournal of diabetes research2025

SGLT2 Inhibitor and GLP-1 Receptor Agonist Prescriptions in Newly Diagnosed Type 2 Diabetes Patients With Cardiorenal Risks: A Cross-Sectional Study.

Frank Müller, Michael J Bouthillier, Omayma Alshaarawy, Hend Azhary, Harland T Holman

Abstract read
In one paragraph

Article in Journal of diabetes research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Frank MüllerDepartment of Family Medicine, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA.ORCID https://orcid.org/0000-0002-9496-9423
Michael J BouthillierDepartment of Family Medicine, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA.
Omayma AlshaarawyDepartment of Family Medicine, College of Human Medicine, Michigan State University, East Lansing, Michigan, USA.ORCID https://orcid.org/0000-0002-5968-0245
Hend AzharyDepartment of Family Medicine, College of Human Medicine, Michigan State University, East Lansing, Michigan, USA.
Harland T HolmanDepartment of Family Medicine, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA.ORCID https://orcid.org/0000-0003-3835-9193

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

Aims: The aim of this study is to evaluate the real-world prescribing patterns of SGLT2 inhibitors and GLP-1 receptor agonists (GLP-1RA) in patients with newly diagnosed Type 2 diabetes (T2DM), particularly among those with high cardiovascular risks or chronic kidney disease, and to identify demographic, clinical, and system-level factors associated with receiving these medications. Materials and Methods: This cross-sectional study analyzed electronic medical records (EMRs) of patients with newly diagnosed T2DM from 60 primary care clinics in West Michigan between April 2021 and January 2023. We assessed the documented prescription rates of SGLT2 inhibitors and GLP-1RAs within 3 months of diagnosis based on EMRs, particularly in high-risk subgroups. Results: Overall, 19.9% of Conclusions: Despite guideline recommendations, SGLT2 inhibitors and GLP-1RAs are prescribed to only a minority of patients with newly diagnosed T2DM, even among those with clear indications. Efforts to improve guideline-adherent care in primary care settings are needed.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Glucagon-Like Peptide-1 Receptor AgonistsHypoglycemic AgentsPractice Patterns, Physicians'Renal Insufficiency, ChronicSodium-Glucose Transporter 2 InhibitorsAgedCross-Sectional StudiesDrug PrescriptionsFemaleHumansMaleMiddle AgedRisk FactorsGlucagon-Like Peptide-1 Receptor AgonistsHypoglycemic AgentsSodium-Glucose Transporter 2 Inhibitors

Identifiers

PMID41220901
PMCPMC12602036

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.