ArticlePlastic and reconstructive surgery. Global open2025
The Association of Hand Dominance With the Development of Breast Cancer-related Lymphedema After Mastectomy: A Retrospective Analysis.
Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Impact of chemotherapy on breast cancer-related lymphedema: a retrospective study.Frontiers in oncology · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Risk factors for developing breast cancer-related lymphedema (BCRL) are well studied, but little is known about the effect of hand dominance (HD). This study aimed to investigate the relationship between HD and postmastectomy BCRL for unilateral breast cancer (BC). Because BCRL treatment involves movement of the affected limb, we postulated that the inherently increased use of a dominant upper extremity may be protective against BCRL. Methods: A retrospective cohort study of female patients with unilateral BC who underwent mastectomy at a single institution between 2012 and 2022 was performed. BCRL was confirmed by a certified lymphedema therapist. The laterality of HD and BC was categorized as ipsilateral or contralateral. Results: Of the 266 patients included in the analysis, 70 (26.3%) developed BCRL. A greater proportion of patients with HD contralateral BC developed BCRL (30.3% versus 22.4%; Conclusions: Although a greater proportion of patients with contralateral HD and BC developed BCRL, our results demonstrated no statistically significant relationship. Known risk factors such as increased number of lymph nodes removed and adjuvant radiation therapy were significantly associated with BCRL. Further studies including larger and multicenter populations are required to comprehensively elucidate the relationship between HD and BCRL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.