Catalytic enantioselective synthesis of selenium-containing atropisomers via C-Se bond formations.

Qi-Sen Gao, Zheng-Wei Wei, Zhi-Min Chen

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Review in Beilstein journal of organic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 authors.

Qi-Sen Gao *State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.

Zheng-Wei Wei *State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.

Zhi-Min ChenState Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.ORCID https://orcid.org/0000-0002-6988-8955

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6 · The paper itself

Abstract

Atropisomers are not only prevalent in biologically active natural products and pharmaceuticals, but they have also garnered increasing attention for their effectiveness as ligands and catalysts in the field of catalytic asymmetric synthesis. Asymmetric catalysis serves as a key strategy for the enantioselective synthesis of atropisomers, and significant progress has been made in recent years. However, selenium-containing atropisomers have long remained underexplored as synthetic targets, and only in recent years have they begun to attract increasing attention from the community. Recently, several synthetic approaches for constructing selenium-containing atropisomers have been reported, such as C-H selenylation of arenes, selenosulfonylation of vinylidene

Indexed as

asymmetric catalysisatropisomerchiral selenium-containing compoundC–Se bond formation

Identifiers

PMID41220837

DOI10.3762/bjoc.21.186

PMCPMC12599392

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