Evidence map›Paper›PMID 41220834›Full record

ArticleBeilstein journal of organic chemistry2025

The high potential of methyl laurate as a recyclable competitor to conventional toxic solvents in [3 + 2] cycloaddition reactions.

Ayhan Yıldırım, Mustafa Göker

Abstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ayhan YıldırımDepartment of Chemistry, Bursa Uludağ University, Bursa 16059, Turkey.ORCID https://orcid.org/0000-0002-2328-9754
Mustafa GökerDepartment of Chemistry, Bursa Uludağ University, Bursa 16059, Turkey.ORCID https://orcid.org/0000-0003-4667-1670

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, 21 fused isoxazolidines were synthesized in yields ranging from good to excellent. Methyl laurate was identified as the easily accessible optimal solvent medium for the reaction, and the related compounds were obtained through straightforward isolation techniques in a relatively short time frame (5-80 minutes). A comprehensive investigation was conducted utilizing various web platforms, encompassing ecological and environmental risk assessments, toxicity, pesticide similarity, and biodegradability of methyl laurate in comparison with a series of conventional organic solvents, water, some fatty acids and their derivatives. The findings of this investigation revealed that methyl laurate exhibited better green solvent properties when evaluated against other solvents.

Indexed as

cycloadditionfused isoxazolidinesrenewable solventreusable solventtrans-diastereoselectivity

Identifiers

PMID41220834
PMCPMC12599400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.