Evidence map›Paper›PMID 41220829›Full record

ArticleERJ open research2025

Chronic cough and chronic pruritus in older adults: a population-based cross-sectional study.

Juliette F Bollemeijer, Sebastian Riemann, Hok Bing Thio, Tamar E C Nijsten, Guy Brusselle, Luba M Pardo

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juliette F BollemeijerDepartment of Dermatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-2350-9526
Sebastian RiemannDepartment of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.ORCID https://orcid.org/0000-0003-1184-7234
Hok Bing ThioDepartment of Dermatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-5095-4281
Tamar E C NijstenDepartment of Dermatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-9940-2875
Guy BrusselleDepartment of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.ORCID https://orcid.org/0000-0001-7021-8505
Luba M PardoDepartment of Dermatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-0684-3175

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic pruritus (CP) and chronic cough (CC) are prevalent conditions with shared underlying mechanisms, including neuronal sensitisation and inflammation. While previous studies identified associations between pruritus and CC, limited data exist on their interplay when accounting for confounders such as smoking and asthma. Methods: This cross-sectional study analysed middle-aged and older participants from a population-based cohort, the Rotterdam Study. Logistic regression models assessed associations between demographic and lifestyle factors ( Results: In total, 4364 participants (age range 48-99 years, median age 71; 58.8% women) were included. Persistent CC was strongly associated with CP, doubling the odds in multivariable analyses (OR 2.07, 95% CI 1.43-3.00). Smoking was independently associated with CP, with the highest odds in current smokers (OR 1.46, 95% CI 1.10-1.92). The association between persistent CC and CP remained robust across all sensitivity analyses. Conclusions: Persistent CC is strongly associated with CP, emphasising shared pathogenic mechanisms. Smoking emerged as a modifiable risk factor for CP. Longitudinal studies are needed to establish causality and optimise therapeutic and management strategies.

Identifiers

PMID41220829
PMCPMC12598587

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.