Evidence map›Paper›PMID 41220815›Full record

ArticleERJ open research2025

The impact of air pollution on active tuberculosis development from latent tuberculosis infection in rural China: 10-year follow-up of a cohort study.

Yuanzhi Di, Henan Xin, Xuefang Cao, Hongzhi Li, Weitao Duan, Aiwei He, Jun Liang, Limei Zhu, Boxuan Feng, Yijun He and 22 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Yuanzhi DiNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Henan XinNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xuefang CaoNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hongzhi LiZhengzhou Sixth People's Hospital, Zhengzhou, China.
Weitao DuanZhongmu County Center for Disease Control and Prevention, Zhongmu, China.
Aiwei HeGansu Provincial Center for Disease Control and Prevention, Lanzhou, China.
Jun LiangHunan Provincial Institute of Tuberculosis Prevention and Control, Changsha, China.
Limei ZhuJiangsu Provincial Center for Diseases Control and Prevention, Nanjing, China.
Boxuan FengNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yijun HeNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lingyu ShenNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Juanjuan HuangNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zisen LiuZhongmu County Center for Disease Control and Prevention, Zhongmu, China.
Fang LiuGansu Provincial Center for Disease Control and Prevention, Lanzhou, China.
Shumin YangGansu Provincial Center for Disease Control and Prevention, Lanzhou, China.
Zuhui XuHunan Provincial Institute of Tuberculosis Prevention and Control, Changsha, China.
Cheng ChenJiangsu Provincial Center for Diseases Control and Prevention, Nanjing, China.
Bin ZhangZhongmu County Center for Disease Control and Prevention, Zhongmu, China.
Jiaoxia YanZhongmu County Center for Disease Control and Prevention, Zhongmu, China.
Yanchun LiangLongxi County Center for Disease Control and Prevention, Longxi, China.
Rong LiuXiangtan County Center for Disease Control and Prevention, Xiangtan, China.
Tao ZhuDanyang City Center for Disease Control and Prevention, Danyang, China.
Fei ShenZhengzhou Sixth People's Hospital, Zhengzhou, China.
Tonglei GuoNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zihan LiNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jianguo LiangNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yaqi ZhaoNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liqiong BaiHunan Provincial Institute of Tuberculosis Prevention and Control, Changsha, China.
Wei LuJiangsu Provincial Center for Diseases Control and Prevention, Nanjing, China.
Qi JinNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jiang DuNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lei GaoNHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of the study was to investigate the impact of major air pollutants on the development of tuberculosis (TB) among adults with latent tuberculosis infection (LTBI) in rural areas in China. Methods: Based on a population-based multicentre cohort study conducted since 2013, we aimed to examine the associations between various air pollutants and the risk of active TB development from LTBI. The estimates were assessed using time-dependent Cox regression models, with nonlinearity evaluated by restricted cubic splines. The China High Air Pollutants datasets were used to feature high-resolution, high-quality, near-surface air pollution data in China. Results: A total of 20 869 participants were followed for 10 years, and 185 incident TB cases were identified. Long-term exposure to PM Discussion: Long-term exposure to air pollutants increased the risk of active TB development from LTBI, highlighting the importance of air pollution control in LTBI management allowing for regional and demographic differences.

Identifiers

PMID41220815
PMCPMC12598598

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.