ReviewMolecular and clinical oncology2025
Analysis of the role of RNA regulatory networks in cancer treatment: Mechanisms, applications and future prospects (Review).
Review in Molecular and clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Liquid Biopsy-Based Metabolomics in Epithelial Ovarian Cancer: Challenges, Methodological Advances and Translational Considerations.Diagnostics (Basel, Switzerland) · 2026Review
- Regulatory Variants in the KRAS 3'UTR and Intron 2 Are Associated with Breast Cancer Susceptibility Through Independent and Combinatorial Effects in a Mexican Population.Biomedicines · 2026Article
- Rewriting Tumor Entry Rules: Microfluidic Polyplexes and Tumor-Penetrating Strategies-A Literature Review.Pharmaceutics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RNA regulatory networks play a central role in cancer development and progression, influencing key biological processes such as cell cycle control, proliferation, apoptosis and tumor microenvironment interactions. MicroRNA (miR) variants, specifically isomiRs, have emerged as a novel research focus due to their altered target specificity and cancer-specific expression patterns, highlighting their potential as diagnostic markers and therapeutic targets. Additionally, advanced technologies such as single-cell sequencing and CRISPR screening offer novel avenues to dissect the complexity of RNA networks and identify key regulators for personalized therapy. The present review provides an integrative overview of RNA regulatory mechanisms, with a particular focus on the functional dynamics of isomiRs and competing endogenous RNA networks. Finally, the translational potential of isomiRs in precision oncology is described and key challenges and future directions in the field are outlined.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.