ArticleEuropean oral research2025
The impact of maleic acid, carbohydrate-derived fulvic acid, and ethylenediaminetetraacetic acid on the flexural strength and modulus of elasticity of human radicular dentin: an in vitro study.
Article in European oral research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This study aimed to evaluate the impact of ethylenediamine tetra-acetic acid (EDTA), carbohydrate-derived fulvic acid (CHD-FA), and maleic acid (MA) on the flexural strength (FS) and modulus of elasticity (ME) of human radicular dentin. Materials and methods: Fifteen freshly extracted human mandibular premolars with single roots and single canals were selected. The teeth were decoronated 2 mm below the cementoenamel junction (CEJ), and the roots were sectioned into buccal and lingual halves. Each half was used to prepare two standardized plano-parallel dentin bars (7 mm in length × 1 mm in width × 1 mm in height). The samples were then divided into four groups and immersed in their respective irrigating solutions for 5 minutes: saline (control), maleic acid, CHD-FA, and EDTA. Subsequently, FS and ME were evaluated using a three-point bending test. Results: Both EDTA and maleic acid reduced the FS and ME of radicular dentin. However, the study demonstrated that higher mean values for FS and ME were recorded in the CHD-FA and saline (control) groups compared to the EDTA and maleic acid groups. Conclusion: CHD-FA is recommended as an endodontic irrigant, as it does not compromise the mechanical properties of radicular dentin, specifically FS and ME.
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