Evidence map›Paper›PMID 41220574›Full record

ArticleEuropean oral research2025

The impact of maleic acid, carbohydrate-derived fulvic acid, and ethylenediaminetetraacetic acid on the flexural strength and modulus of elasticity of human radicular dentin: an in vitro study.

Loganathan Saatwika, Venkatachalam Prakash, Suresh Mitthra, Rajasekar Parthasarathy, Alagarsamy Venkatesh, Krishnamurthy Madhuram, Pachaiyappan Elangovan Mukundan

Abstract read
In one paragraph

Article in European oral research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Loganathan SaatwikaBangalore Institute of Dental Sciences, Department of Conservative Dentistry & Endodontics, Bangalore, India.
Venkatachalam PrakashSree Balaji Dental College & Hospital, Department of Conservative Dentistry & Endodontics, Chennai, India.
Suresh MitthraSRM Kattankulathur Dental College & Hospital, Department of Conservative Dentistry & Endodontics, Chennai, India.
Rajasekar ParthasarathySree Balaji Dental College & Hospital, Department of Conservative Dentistry & Endodontics, Chennai, India.
Alagarsamy VenkateshDepartment of Conservative Dentistry & Endodontics, Sree Balaji Dental College & Hospital, ChennaiIndia.
Krishnamurthy MadhuramDepartment of Conservative Dentistry & Endodontics, Karpaga Vinayaga Institute of Dental Sciences, ChengalpattuIndia.
Pachaiyappan Elangovan MukundanDepartment of Conservative Dentistry & Endodontics, Madha Dental college & Hospital, Chennai India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the impact of ethylenediamine tetra-acetic acid (EDTA), carbohydrate-derived fulvic acid (CHD-FA), and maleic acid (MA) on the flexural strength (FS) and modulus of elasticity (ME) of human radicular dentin. Materials and methods: Fifteen freshly extracted human mandibular premolars with single roots and single canals were selected. The teeth were decoronated 2 mm below the cementoenamel junction (CEJ), and the roots were sectioned into buccal and lingual halves. Each half was used to prepare two standardized plano-parallel dentin bars (7 mm in length × 1 mm in width × 1 mm in height). The samples were then divided into four groups and immersed in their respective irrigating solutions for 5 minutes: saline (control), maleic acid, CHD-FA, and EDTA. Subsequently, FS and ME were evaluated using a three-point bending test. Results: Both EDTA and maleic acid reduced the FS and ME of radicular dentin. However, the study demonstrated that higher mean values for FS and ME were recorded in the CHD-FA and saline (control) groups compared to the EDTA and maleic acid groups. Conclusion: CHD-FA is recommended as an endodontic irrigant, as it does not compromise the mechanical properties of radicular dentin, specifically FS and ME.

Indexed as

CHD-FAEDTAflexural strengthmaleic acidmodulus of elasticityRadicular dentin

Identifiers

PMID41220574
PMCPMC12599545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.