ArticleJMA journal2025
Ichthyosis Uteri Mimicking Endometrial Cancer with Apparent Myometrial Invasion.
Article in JMA journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Ichthyosis uteri is a rare benign condition characterized by extensive squamous metaplasia of the endometrium. We present an unusual case of ichthyosis uteri with radiological features mimicking myometrial invasion of endometrial cancer, occurring in a 50-year-old postmenopausal woman who presented with persistent abnormal vaginal bleeding. Laboratory findings revealed elevated serum squamous cell carcinoma (SCC) antigen level of 11.5 ng/mL. Magnetic resonance imaging (MRI) demonstrated an intrauterine lesion with apparent myometrial invasion, initially suggesting the International Federation of Gynecology and Obstetrics stage IA endometrial cancer. The lesion showed low signal intensity on the T2-weighted image compared to normal endometrium and weak enhancement on the contrast-enhanced T1-weighted image. While the lesion showed high signal intensity on diffusion-weighted imaging, the apparent diffusion coefficient value (0.96 × 10
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