ReviewBiomaterials research2025
Architectural Design of Biomaterial Scaffolds for Hematopoietic Stem Cell Culture.
Review in Biomaterials research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, biomaterials have been developed for ex vivo expansion of hematopoietic stem cells (HSCs). HSCs exist in highly specialized niches in the bone marrow and are extremely sensitive to their microenvironment; therefore, this review focuses on the architecture of biomaterials and its effects on HSC culture. Herein, we describe the chemical and physical components of the HSC's niche that can be used to inform the design of biomaterials. We then summarize the effects of surface topography, structural properties, and chemical composition of biomaterials on HSC culture. Subsequently, we identify the gaps and challenges in HSC culture, informing the potential future directions that studying HSC culture on biomaterials can take.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.