ArticleCureus2025
Severe Babesiosis With Multifactorial Hemolysis and Pulmonary Complications in an Asplenic Patient at a Tertiary Cancer Center.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Babesiosis is a tick-borne protozoal infection that can cause life-threatening disease in asplenic or immunocompromised patients. We report a 71-year-old woman with prior distal pancreatectomy and splenectomy who developed severe babesiosis complicated by pulmonary involvement and complement-mediated hemolysis. Initial therapy with clindamycin-atovaquone and partial exchange transfusion was required due to a reported azithromycin allergy; following successful rechallenge, she tolerated guideline-based azithromycin-atovaquone. Despite parasite clearance, she developed complement-mediated hemolysis confirmed by a complement C3-positive, IgG-negative direct antiglobulin test. A 71-year-old woman with a history of distal pancreatectomy and splenectomy for pancreatic carcinoma (without recurrence) presented from upstate New York with one week of fever, chills, headache, fatigue, and myalgias. She denied a known tick bite but reported a small pink skin lesion. Initial laboratory evaluation revealed thrombocytopenia, transaminitis, and hyperbilirubinemia; hepatitis, Epstein-Barr virus, and cytomegalovirus testing were negative, while
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